Comparative Study of the Possibilities of Bone Scintigraphy and Magnetic Resonance Imaging of the Whole Body in the Diagnosis of Bone Metastases

Purpose. Compare the characteristics of MRI techniques and whole-body bone scintigraphy in the detection of bone metastases in primary malignant tumors of the most frequent sites. Materials and methods. 29 patients with malignant tumors of different localization and suspected secondary bone lesions were examined at “RNTSRR”. All patients underwent bone scan to gamma camera Nucline DHW using mono-and diphosphates of Tc-99m activity of 370-600 MBq, as well as MRI “whole body” for magnetic resonance imaging “Atlas” 1.5 T, and “Signa” 1.5 T The diagnosis of secondary bone lesions was further confirmed by the data MSCT or supervision for 6 months. Results. Metastatic bone lesions were present in 21 (72.4%) patients, benign nature were identified at 8 patients (27.6%) patients. According to the results of the use of MRI techniques “whole body” was placed 1 false-negative and false-positive diagnosis 2, the sensitivity of techniques was 95.2% (20/21), specificity of 75% (6.8). According to bone scan were mentioned 3 false-negative results, and 3 falsepositive, the sensitivity was 85.7% technique (18/21), specificity - 62.5% (8.5). The accuracy of the technique of the whole body MRI was 89.6% (26/29), bone scintigraphy - 79.3% (23/29). Conclusions. MRI “whole body” is a more objective procedure than bone scan, due to a more accurate visualization of anatomical zones. Using MRI “whole body” for suspected secondary bone disease can reduce the need for additional diagnostic studies. MRI “whole body” is no-radiation procedure, but it is technically difficult and may not be performed at all equipment, which leads to increased cost of study.

МРТ всего тела, остеосцинтиграфия, метастазы в кости, онкология, MRI “whole body”, bone scan, bone metastases, oncology

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