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Ultrasonic diagnosis of soft tissue sarcomas using functional vascular test

https://doi.org/10.24835/1607-0763-2019-3-126-132

Abstract

The purpose of the research is to find additional diagnostic tools that allow you to specify the nature of soft tissue lesions, differentiate between benign and malignant processes this localization.
Materials and methods. Using multiparametric echography surveyed 514 patients with malignant (243 or 55.7%) and benign (193 or 44.3%) tumor, as well as non-tumor (78 or 15.2%) diseases. In all cases, used while rendering, color Doppler mapping, power Doppler blood flow spectral characteristics of the studied zone changes. In 87 (16.9%) observations applied functional vascular test.
The results. Calculation of indicators diagnostic informative at diagnostics of sarcomas in relation to complex high without the use of vascular test and when you post data showed an increase in using it specificity and diagnostic accuracy stability in the total sensitivity of the entire complex. Sensitivity respectively amounted to 92.7% and 92.7%, specificity – 87.1% and 98.9%, accuracy-84.8% and 91.1% (inclusion in consideration of inflammatory processes led to the authenticity of the results obtained).
Conclusion. Vascular test improves diagnostic high informativeness of the complex, but it can be usefully applied to exclude non-tumorous changes and accounting possible differences in differentiation of different constituent parts neoplasm.

About the Authors

A. N. Zaitsev
N.N. Petrov National Medical Research Oncology Center
Russian Federation

cand. of med. sci, senior researcher

197758, St. Petersburg, Pesochny-2, Leningradskaya str., 68

Phone: +7-911-231-25-20



I. I. Semenov
N.N. Petrov National Medical Research Oncology Center
Russian Federation

doct. of med. sci., senior researcher

197758, St. Petersburg, Pesochny-2, Leningradskaya str., 68



References

1. Shipulo M.G. A practical guide to ultrasound Diagnostics. M.: Vysshaya shkola,1995. 1240 p.

2. Zajcev V.N., Mishhenko A.V., Semjonov I.I. While Ultrasound and Doppler echocardiography in the diagnostic algorithms in soft tissue tumors. Vestnik Sankt-Peterburgskogo universiteta. Ser. 11. 2013; .2: 161–169.

3. Riishede I., Ewertsen C., Carlsen J., Petersen M.M., Jensen F., Nielsen M.B. Elastography for Prediction of Malignancy in Soft Tissue Tumours – Preliminary Results. Ultraschall in Med. 2015; 36 (04): 369–374.

4. Frolova I.G., Kotova O.V., Tjukalov Ju.M., Velichko S.A., Bober' E.E., Starceva Zh.A., Konovalov A.I., Bogoutdinova A.V. Features of ultrasonic method in the diagnosis of soft tissue sarcomas (review of literature). Sibirskij onkologicheskij zhurnal. 2015; 3: 82–89.

5. Trufanov G.E., Pchelin I.G., Vecmadjan E.A. Ultrasound diagnosis of soft tissue tumors. S.Pb.: JeLBI-S.Pb., 2017. 112 p.

6. Morii T., Kishino T., Shimamori N., Motohashi M., Ohnishi H., Honya K., Aoyagi T., Tajima T., Ichimura S. Differential diagnosis between benign and malignant soft tissue tumors utilizing ultrasound parameters. J. Med. Ultrason. 2018; 45 (1): 113–119.

7. Brown J.M., Giaccia A.J. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 1998; 58 (7): 1408–1416.

8. Schmidseder R., Noma H. Microangiographic studies of the squamous cell carcinoma of the oral cavity. 4th Int. Congr. Dento-Maxillo Facial Radiol. Malmo, 1977; Program. and abstr.; 60.

9. Metelica V.I. Handbook of clinical pharmacology of cardiovascular medicines. M.: Medpraktika, 1996. 784 p.

10. Guide to surgery; Eds S. Shvarc, Dzh. Shajers, F. Spenser, V. Husser. SPb.; M.; Har'kov; Minsk, 1999. 880 p.

11. Ruksin V.V. Urgent cardiology. S.Pb.: Nevskij Dialekt–M.: Binom, 1998. 188 p.

12. A practical guide to ultrasound Diagnostics. General ultrasound diagnosis. 2-e izd., pererab. i dop. Ed. V.V. Mit'kov. M.: Vidar, 2011. 720 p.

13. Zaitsev A.N., Reshetnikova T.S. Increasing the efficiency of the diagnosis of pathology of soft tissues by the combined use of thermography and еchography. J. Opt. Technol. 2001; 68 (5): 370–371.

14. Clinical guide to ultrasound Diagnostics. Eds V.V.Mit'kov, M.V. Medvedev. M.: Vidar, 1996. Vol. 2. 408 p.


Review

For citations:


Zaitsev A.N., Semenov I.I. Ultrasonic diagnosis of soft tissue sarcomas using functional vascular test. Medical Visualization. 2019;(3):126-132. (In Russ.) https://doi.org/10.24835/1607-0763-2019-3-126-132

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ISSN 1607-0763 (Print)
ISSN 2408-9516 (Online)