Metastasis of adrenal cortical cancer into the lungs (rare observation)
https://doi.org/10.24835/1607-0763-2018-6-33-39
Abstract
Adrenocortical cancer (ACC) – a neoplasm of the adrenal cortex, which is rare, in 0.02–0.06% of cases. It is characterized by various clinical manifestations in the form of hypercorticism of varying severity and unfavorable prognosis. Typically, a tumor in the form of a node, often with signs of infiltration growth. Some tumors are formed by light and dark cells, there is often significant cellular polymorphism. Malignant tumors of the adrenal cortex have a pronounced tendency to hematogenous metastasis, usually in the lungs, bones and other organs. The article presents a rare clinical case of metastatic lung injury, identified 22 years after the removal of the adrenal malignant tumor (AKP).
About the Authors
N. V. Nudnov
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Nikolay V. Nudnov – doct. of med. sci., Professor
117997 Moscow, Profsoyuznaya str., 86. Phone: +7-985-224-04-68
N. V. Chernichenko
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Nataliay V. Chernichenko – doct. of med. sci., bronchologist, physician of the highest qualification category, leading researcher
Russian Federation
Nataliay V. Chernichenko – doct. of med. sci., bronchologist, physician of the highest qualification category, leading researcher
Ya. Yu. Murzin
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Yaroslav Yu. Murzin – cand. of med. sci., thoracic surgeon-oncologist
Russian Federation
Yaroslav Yu. Murzin – cand. of med. sci., thoracic surgeon-oncologist
O. P. Bliznyukov
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Oleg P. Bliznyukov – doct. of med. sci., Head of the pathoanatomical department
Russian Federation
Oleg P. Bliznyukov – doct. of med. sci., Head of the pathoanatomical department
I. D. Lagkueva
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Irina D. Lagkueva – radiologist, researcher of Russian Scientific Center
Russian Federation
Irina D. Lagkueva – radiologist, researcher of Russian Scientific Center
E. V. Sidorova
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Еlena V. Sidorova – a clinical resident on the specialty in radiology
Russian Federation
Еlena V. Sidorova – a clinical resident on the specialty in radiology
O. V. Fedorova
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Olga V. Fedorova – a clinical resident on the specialty in radiology
Russian Federation
Olga V. Fedorova – a clinical resident on the specialty in radiology
References
1. Beltsevich D.G. Adrenocortical cancer. Urology and Andrology. 2013; 2 (3): 55–61. (In Russian)
2. Stepanova Yu.A., Timina I.E., Ashivkina O.I., Vetsheva N.N., Kosova I.A., Berelavichus S.V. Tumors of the adrenal glands: clinical diagnosis (review of literature). Medical Visualization. 2014; 2: 48–60. (In Russian)
3. Kaprin A.D., Starinsky V.V., Petrova G.V. Malignant neoplasms in Russia in 2016 (morbidity and mortality). M.: MNIOI them. P.A. Herzen is a branch of FGBU “NMIC of Radiology” of the Ministry of Health of Russia, 2018. (In Russian)
4. Wang C., Sun Y., Wu H., Zhao D., Chen J. Distinguishing adrenal cortical carcinomas and adenomas: a study of clinicopathological features and biomarkers. Histopatology. 2014; 64: 567–576.
5. Britvin T.A., Krivosheev A.V., Beloshitsky M.E. Adrenocortical cancer. RMJ (Russian Medical Journal). 2015; 23 (8): 461. (In Russian)
6. Bilimoria K.Y., Shen W.T., Elaraj D., Bentrem D.J., Winchester D.J., Kebebew E., Sturgeon C. Adrenocortical carcinoma in the United States: treatment utilization and prognostic factors. Cancer. 2008; 113 (11): 3130–3136. DOI: 10.1002/cncr.23886.
7. Hou J., Wang H., Zhang G., Ma Z. Diagnosis and Treatment of Multiple Primary Lung Cancer. Zhongguo Fei Ai Za Zhi. 2015; 18 (12): 764–769. DOI: 10.3779/j.issn.1009-3419.2015.12.09.
8. Trakhtenberg A.H. Lung cancer. Moscow: GEOTAR-Media, 2009. 656 p. (In Russian)
9. Tyurin I.E. Lecture “Radiation diagnosis of metastatic lung lesions”. Atmosphere. Pulmonology and allergology. 2011; 1: 22–28. (In Russian)
10. Melnichenko G.A., Stilidi I.S., Alekseev B.Ya., Gorbunova V.A., Beltsevich D.G., Reichman A.O., Kuznetsov N.S., Zhukov N.V., BokhyanV.Yu. Federal clinical guidelines for the diagnosis and treatment of adrenocortical cancer. Problems of endocrinology. 2014; 60 (2): 51–67. DOI: 10.14341 / probl201460251-67. (In Russian)
11. Tikkanen M.J., Sivnla A., Kahri A., Pelkonen R. Recurrent adrenal cortical carcinoma with Cushing’s syndrome: twenty-five-year follow-up of a patient. J. Endocrinol. Invest. 1986; 4: 425–427.
Review
For citations:
Nudnov N.V., Chernichenko N.V., Murzin Ya.Yu., Bliznyukov O.P., Lagkueva I.D., Sidorova E.V., Fedorova O.V. Metastasis of adrenal cortical cancer into the lungs (rare observation). Medical Visualization. 2018;22(6):33-39. (In Russ.) https://doi.org/10.24835/1607-0763-2018-6-33-39
Views:
973
Email this article 