Intravascular Ultrasound Studies and the Vulnerable Atherosclerotic Plaque (Literature Review)
https://doi.org/10.24835/1607-0763-2017-4-82-87
Abstract
The vulnerable plaque is an atherosclerotic plaque which can lead to thrombosis of a coronary artery with development of an acute coronary syndrome. Most myocardial infarctions occur in people with average levels of risk factors and thrombosis mostly originate from lesions that are less severely narrowed. Thus, in most cases, these plaques are clinically silent before the “unheralded” acute event and would not be considered eligible for preventive treatment based on current guidelines. The main question is to identify thrombosis-prone “vulnerable” plaques before they rupture or become destabilized. IVUS is a useful tool in identifying high risk plaque features and vulnerable lesions in patients.
About the Authors
N. A. Kochergin
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Competing Interests:
Russian Federation
Competing Interests:
researcher of laboratory of endovascular diagnosis and treatment of Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo
Sosnoviy blvd., 6, 650002, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russia. Phone: +7-908-952-32-35
A. M. Kochergina
Kemerovo state medical university
Russian Federation
Competing Interests:
Russian Federation
Competing Interests:
cand. of med. sci., researcher of department of cardiology and Cardiac Surgery of Kemerovo state medical university, Kemerovo
References
1. Muller J.E., Tofler G.H., Stone P.H. Circadian variation and triggers of onset of acute cardiovascular disease. Circulation. 1989; 79: 733–743. DOI: 10.1161/01.cir.79.4.733.
2. Naghavi M., Libby P., Falk E. et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation. 2003; 108: 1664–1672. DOI: 10.1161/01.cir.0000087480.94275.97.
3. Akosah K.O., Schaper A., Cogbill C., Schoenfeld P. Preventing myocardial infarction in the young adult in the first place: how do the National Cholesterol Education Panel III guidelines perform? J. Am. Coll. Cardiol. 2003; 41: 1475–1479. DOI: 10.1016/s0735-1097(03)00187-6.
4. Ambrose J., Winters S., Arora R. et al. Angiographic evolution of coronary artery morphology in unstable angina. J. Am. Coll. Cardiol. 1986; 7: 472–478. DOI: 10.1016/s0735-1097(86)80455-7.
5. Little W., Constantinescu M., Applegate R. et al. Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? Circulation. 1988; 78: 1157– 1166. DOI: 10.1161/01.cir.78.5.1157.
6. Hackett D., Davies G., Maseri A. Preexisting coronary stenoses in patients with first myocardial infarction are not necessarily severe. Eur. Heart J. 1988; 9: 1317–1323. DOI: 10.1093/oxfordjournals.eurheartj.a062449.
7. Giroud D., Li J.M., Urban P. et al. Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography. Am. J. Cardiol. 1992; 69: 729–732. DOI: 10.1016/0002-9149(92)90495-k.
8. Schoenhagen P., Ziada K.M., Kapadia S.R. et al. Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study. Circulation. 2000; 101: 598–603. DOI: 10.1161/01.cir.101.6.598.
9. Sano K., Kawasaki M., Ishihara Y. et al. Assessment of vulnerable plaques causing acute coronary syndrome using integrated backscatter intravascular ultrasound. J. Am. Coll. Cardiol. 2006; 47: 734–741. DOI: 10.1016/j.jacc.2005.09.061.
10. Okura H., Kobayashi Y., Sumitsuji S. et al. Effect of culpritlesion remodeling versus plaque rupture on three-year outcome in patients with acute coronary syndrome. Am. J. Cardiol. 2009; 103: 791–795. DOI: 10.1016/j.amjcard.2008.11.030.
11. Motoyama S., Sarai M., Harigaya H. et al. Computed tomographic angiography characteristics of atherosclerotic plaques subsequently resulting in acute coronary syndrome. J. Am. Coll. Cardiol. 2009; 54: 49–57. DOI: 10.1016/j.jacc.2009.02.068.
12. Alsheikh-Ali A.A., Kitsios G.D., Balk E.M. et al. The vulnerable atherosclerotic plaque: scope of the literature. Ann. Intern. Med. 2010; 153: 387–395. DOI: 10.7326/0003-4819-153-6-201009210-00272.
13. Virmani R., Burke A.P., Farb A., Kolodgie F.D. Pathology of the vulnerable plaque. J. Am. Coll. Cardiol. 2006; 47: C13–18. DOI: 10.1016/j.jacc.2005.10.065.
14. Nasu K., Tsuchikane E., Katoh O. et al. Impact of intramural thrombus in coronary arteries on the accuracy of tissue characterization by in vivo intravascular ultrasound radiofrequency data analysis. Am. J. Cardiol. 2008; 101: 1079–1083. DOI: 10.1016/j.amjcard.2007.11.064.
15. Maehara A., Cristea E., Mintz G. et al. Definitions and Methodology for the Grayscale and Radiofrequency Intravascular Ultrasound and Coronary Angiographic Analyses. J. Am. Coll. Cardiol. Cardiovasc. Imaging. 2012; 5 (3): 1-9. DOI: 10.1016/j.jcmg.2011.11.019.
16. Prati F., Guagliumi G., Mintz G. et al. Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures. Eur. Heart J. 2010; 33: 2513–2520. DOI: 10.1093/eurheartj/ehs095.
17. Hoang V., Grounds J., Pham D. et al. The Role of Intracoronary Plaque Imaging with Intravascular Ultrasound, Optical Coherence Tomography, and Near- Infrared Spectroscopy in Patients with Coronary Artery Disease. Curr. Atheroscler. Rep. 2016; 18 (9). DOI: 10.1007/s11883-016-0607-0.
18. Kubo T., Imanishi T., Takarada S. et al. Assessment of culprit lesion morphology in acute myocardial infarction: ability of optical coherence tomography compared with intravascular ultrasound and coronary angioscopy. J. Am. Coll. Cardiol. 2007; 50: 933–939. DOI: 10.1016/j.jacc.2007.04.082.
19. Sawada T., Shite J., Garcia-Garcia H. et al. Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thincap fibroatheroma. Eur. Heart J. 2008; 29: 1136–1146. DOI: 10.1093/eurheartj/ehn132.
20. Brugaletta S., Garcia-Garcia H., Serruys P. et al. NIRS and IVUS for characterization of atherosclerosis in patients undergoing coronary angiography. JACC Cardiovasc. Imaging. 2011; 4: 647–655. DOI: 10.1016/j.jcmg.2011.03.013.
21. Nair A., Margolis M.P., Kuban B.D., Vince D.G. Automated coronary plaque characterisation with intravascular ultrasound backscatter: ex vivo validation. Euro Intervention. 2007; 3: 113–120. DOI: 10.1121/1.4786083.
22. Hiro T. Three stars of the constellation of color intravascular ultrasound in the space of tissue characterization of coronary plaque. J. Cardiol. 2013; 61: 186–187. DOI: 10.1016/j.jjcc.2013.01.001.
23. Cascón-Pérez J., de la Torre-Hernández J., Ruiz-Abellón M. et al. Characteristics of culprit atheromatous plaques obtained in vivo by intravascular ultrasound radiofrequency analysis: Results from the CULPLAC study. Am. Heart J. 2013; 165 (3): 400–407. DOI: 10.1016/j.ahj.2012.12.011.
24. Zhao Z., Witzenbichler B., Mintz G. et al. Dynamic nature of nonculprit coronary artery lesion morphology in STEMI: a serial IVUS analysis from the HORIZONS-AMI trial. J. Am. Coll. Cardiol. Cardiovasc. Imaging. 2013; 6 (1): 86–95. DOI: 10.1016/j.jcmg.2012.08.010.
25. Stone P., Saito S., Takahashi S. et al. Prediction of Progression of Coronary Artery Disease and Clinical Outcomes Using Vascular Profiling of Endothelial Shear Stress and Arterial Plaque Characteristics: The PREDICTION Study. Circulation. 2012; 126: 172–181. DOI: 10.1161/circulationaha.112.096438.
26. Kaul S., Diamond G.A. Improved prospects for IVUS in identifying vulnerable plaques? JACC Cardiovasc Imaging. 2012; 5 (3 Suppl.): S106–110. DOI: 10.1016/j.jcmg.2012.02.00.
27. Calvert P., Obaid D., O'Sullivan M. et al. Association between IVUS findings and adverse outcomes in patients with coronary artery disease: the VIVA (VH-IVUS in Vulnerable Atherosclerosis) Study. JACC Cardiovasc. Imaging. 2011; 4: 894–901. DOI: 10.1016/j.jcmg.2011.05.005.
28. Sinclair H., Veerasamy M., Bourantas C. et al. The Role of Virtual Histology Intravascular Ultrasound in the Identification of Coronary Artery Plaque Vulnerability in Acute Coronary Syndromes. Cardiol. Rev. 2016; 24 (6): 303–309. DOI: 10.1097/CRD.0000000000000100.
29. Cheng J., Garcia-Garcia H., de Boer S. et al. In vivo detection of high-risk coronary plaques by radiofrequency intravascular ultrasound and ardiovascular outcome: results of the ATHEROREMO-IVUS study. Eur. Heart J. 2014; 35: 639–647. DOI: 10.1093/eurheartj/eht484.
30. Battes L., Cheng J., Oemrawsingh R. et al. Circulating cytokines in relation to the extent and composition of coronary atherosclerosis: results from the ATHEROREMOIVUS study. Atherosclerosis. 2014; 236 (1): 18–24. DOI: 10.1016/j.atherosclerosis.2014.06.010.
31. Cheng J., Oemrawsingh R., Garcia-Garcia H. et al. Relation of C-Reactive Protein to Coronary Plaque Characteristics on Grayscale, Radiofrequency Intravascular Ultrasound, and Cardiovascular Outcome in Patients With Acute Coronary Syndrome or Stable Angina Pectoris (from the ATHEROREMO-IVUS Study). Am. J. Cardiol. 2014; 114: 1497–1503. DOI: 10.1016/j.amjcard.2014.08.013.
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For citations:
Kochergin N.A., Kochergina A.M. Intravascular Ultrasound Studies and the Vulnerable Atherosclerotic Plaque (Literature Review). Medical Visualization. 2017;(4):82-87. (In Russ.) https://doi.org/10.24835/1607-0763-2017-4-82-87
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