Features of Magnetic Resonance Tomography Semiotics of Temporomandibular Joint in Patients with Distal Occlusion in Various Clinical Variants of Temporomandibular Joint Dysfunction

Aim: to study stigmatization of connective tissue dysplasia and androgenic profiles as potential markers associated with temporomandibular joint disorders, compared with magnetic resonance tomography imaging of the temporomandibular joint in patients with different clinical variants of its dysfunction. Materials and methods. 40 patients with distal occlusion 35 women (87.5%) and 5 men (12.5%) and dysfunction of the temporomandibular joint (from mild to severe). The clinical examination included: evaluation of connective tissue dysplastic stigmatization; Magnetic resonance tomography on Vantage Atlas-X 1.5 T, hormones concentrations estimation by Enzyme immunoassay: testosterone-estradiol binding globulin, total and free testosterone, estradiol, free androgen index. All patients were devided into two groups according to the Scale of severness of temporomandibular “joint dysfunction syndrome”: the 1-st mild group (0-6 score) included 18 patients (45,0%) with less than 3 displastic stigmatization; the 2nd severe group (1012 scores) - 22 patients with 6 and more dysplastic stigmatization. Results. In the first group of mildly symptomatic patients without complaints in 56.6% cases a combination of up to 2, in 44.4% - up to three clinical manifestations, the temporomandibular joint dysfunction was found. Signs of intra violations in each fourth case reflected changes, characteristic of early stages of osteoarthritis. The combination frequency of over 3 clinical manifestations in patients of the second group (100%), combined with magnetic resonance imaging of soft tissue and bone changes in intra-changes with the hallmark of chronic synovitis - the presence of a pathological effusion in 45.5% of cases. The detected significant increase in androgens in patients of the second group correlated with the severity of the studied disease and the degree of morphological changes. Conclusion. The extent of anatomical and functional changes in the joint correlates with increasing frequency of detection, bilateral localization and involvement into the process of other joint elements (bone, soft tissue, muscular system), as well as phenotypic burdened stigma DST and hyperandrogenism in patients with distal occlusion.

дисфункции височно-нижнечелюстного сустава, дисплазии соединительной ткани, андрогенный профиль, temporomandibular joint dysfunction, connective tissue dysplasia, androgen level

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