Diagnostics of Breast Lesions. A Fine-Needle Aspiration Biopsy or a Core-Biopsy?

The purpose: to estimate and compare sensitivity and accuracy fine-needle aspiration biopsy (FNA) and corebiopsy (CB) in breast lesion's diagnostics of breast lesions. Material and methods. The results of 1496 biopsies performed to patients for 18 months since 2013 were analyzed. Punctures of lesion were carried out with ultrasound guidance by a syringe of 20 ml (20 gauge needle). A corebiopsy was performed under stereotaxic and ultrasound guidance with used automatic systems (Bard Magnum, 14 gauge needles, 130 mm) and semi-automatic systems for biopsy (Somatex, 14 gauge needles, 100 mm). Ultrasound visualization was carried out on system Hitachi Preirus with use of the linear gauge 10-13 MGz, the stereotaxic guidance biopsy was carried out on digital mammography GE Essential with system for a stereotaxic biopsy. Results. 852 (60%) patients with the benign lesions of breast and 644 (40%) patients with the malignant we survey. Results were estimated depending on the size of lesions. Sensitivity, specificity and accuracy FNA under ultrasound guidance for mass less than 1 sm and from 1 to 2 sm have made accordingly 67% and 86%; 93% and 99%; 85% and 95.5%. PPV - 80% and 98%; PNV - 87% and 95%. At the size of mass more than 2 cm sensitivity and specificity FNA has been 100%. Sensitivity and specificity of core-biopsy under ultrasound guidance for mass less than 1 cm was 94% and 100% accordingly. Under radiological guidance - 97% and 100%. For abnormalities more than 1 cm Core-biopsy was informative in 100% of cases for abnormalities more than 1 cm . Conclusion. Verification of breast mass abnormalities less than 2 sm to spend core-biopsy under ultrasound guidance, and calcifications or architectural distortion under stereotaxic guidance more effectively. Sensitivity FNA in diagnostics of mass more than 2 sm under guidance reaches 100%.

молочная железа, рак молочной железы, диагностика, трепан-биопсия, ТАБ, аспирационная биопсия, breast, cancer, diagnostics, core-biopsy, FNA, aspiration biopsy

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