^99mTc-MIBI SPECT and SPECT/CT in Diagnostics of Sternum Osteomyelitis in Patients after Sternotomy

Purpose: assessrnent of^99mTc-MIBI SPECT and SPECT/ CT capabilities in diagnoses of sternurn osteornyelitis in patients after sternotorny. Material and methods. 28 patients with (suspected postsurgical sternurn osteornyelitis (n = 21, 75.0%) and patients with neoplastic, inflarnrnatory or other diseases of lungs or rnediastinurn without sternurn involved (n = 7, 25.0%) were undergone^99mTc-MIBI SPECT and SPECT/CT Results. Scintigraphic sign of sternurn osteornyelitis was pathological intraosseous accurnulation^99mTc-MIBI in sternurn. On basis of this sign sensitivity, specificity, positive and negative predictive values, accuracy of^99mTc-MIBI SPECT were 88.9%, 100.0%, 100.0%, 83.3% and 92.9%, respectively; sensitivity, specificity, positive and negative predictive values, accuracy of SPECT/CT were 94.4, 100.0, 100.0, 90.9 and 96.4%, respectively. Cause of the false-negative results of^99mTc-MIBI SPECT were connective tissue growth in chronic inflarnrnation’s area, and incorrect congruence also between focus of rnarker hyperfixation and soft tissue of anterior chest wall due wide sternurn diastasis in patient with fixation sternurn failure. Through the use of SPECT/CT second false-negative result was avoided. Conclusion.^99mTc-MIBI SPECT and SPECT/CT are perspective and available tools for indication of sternurn osteornyelitis in patients after sternotorny. But sensitivity of SPECT/CT is higher than^99mTc-MIBI SPECT due better spatial congruence between inflarnrnatory focuses and anatomical structures.

ОФЭКТ с 99mТс-МИБИ, ОФЭКТ/КТ остеомиелит грудины, воспалительные процессы, стернотомия, SPECT 99mTc-MIBI, SPECT/CT, sternurn osteornyelitis, inflarnrnatory processes, sternotomy

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