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Evaluation of breast arterial calcification as a predictor coronary artery calcification

https://doi.org/10.24835/1607-0763-986

Abstract

Cardiovascular diseases (CVD) are socially significant diseases and one of the main causes of death among women. There are no effective and uniform screening methods to prevent the prevalence and mortality of CVD. Breast artery calcifications may be one of the available tools for CVD risk stratification. The pathogenesis of calcification of the middle vessel wall, known as Mönckeberg's arteriosclerosis, is different from the pathogenesis of coronary atherosclerosis that coronary arteries. However, research data supports a correlation between breast artery calcifications and risk factors for CVD. These factors include coronary atherosclerosis, detected by CT-coronarography.
Purpose. To assess the prevalence of breast arterial calcification and to determine the association with cardiovascular risk factors, coronary artery calcification, atherosclerosis of brachiocephalic arteries and visceral branches of the abdominal aorta.
Material and methods. 21 patients were hospitalized in the cardiology department. The patients underwent digital mammography to detect breast arterial calcifications. All patients also underwent CT coronary angiography with angiography of the abdominal aorta.
Results. The use of the Wilcoxon-Mann-Whitney W-test with an abnormal distribution showed a correlation between the breast arterial calcifications and the calcium index (p = 0.0028), coronary artery stenosis (p = 0.040), calcification of the thoracic aorta wall (p = 0.035) and stenosis of the visceral branches of the abdominal aorta (p = 0.037).
Conclusions. The breast arterial calcifications correlates with a more frequent detection of calcifications in the walls of the coronary arteries and a higher calcium index.

About the Authors

D. A. Bazhenova
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Daria A. Bazhenova – PhD Student at Radiology department; Radiologist at Radiology department with CT and MRI

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



O. S. Puchkova
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Ol’ga S. Puchkova – Radiologist at Radiology department with CT and MRI

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



O. M. Larina
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Ol’ga M. Larina – Radiologist at Radiology department with CT and MRI

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



E. A. Mershina
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Elena A. Mershina – Cand. of Sci. (Med.), Assistant Professor of Radiology department, Head of Radiology department

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



L. I. Dyachuk
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Larisa I. Dyachuk – cardiologist, head of the cardiology department

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



N. A. Karanadze
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Nino A. Karanadze – cardiologist at cardiology department

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



Y. E. Arutyunova
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Yana E. Arutyunova – cardiologist at cardiology department

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



R. M. Gorbunov
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Roman M. Gorbunov – Ultrasound doctor at the Department of Ultrasound Diagnostics

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



V. E. Sinitsin
Medical Research and Education Center of Lomonosov Moscow State University
Russian Federation

Valentin E. Sinitsin – Doct. of Sci. (Med.), Professor, Head of Radiology department, Chief of Radiology and Radiotherapy Chair, Faculty of Fundamental Medicine

119192, Moscow, Lomonosovsky prospekt, 27-10


Competing Interests:

The authors declare no conflict of interest.



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For citations:


Bazhenova D.A., Puchkova O.S., Larina O.M., Mershina E.A., Dyachuk L.I., Karanadze N.A., Arutyunova Y.E., Gorbunov R.M., Sinitsin V.E. Evaluation of breast arterial calcification as a predictor coronary artery calcification. Medical Visualization. 2022;26(2):113-124. (In Russ.) https://doi.org/10.24835/1607-0763-986

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