Evaluation of fMRI counting task efficiency for normal brain functional connectivity analisys during executive function examination
S, N. Morozova,
E. I. Kremneva,
Z. Sh. Gadzhieva,
B. M. Akhmetzyanov,
M. V. Krotenkova,
L. A. Dobrynina https://doi.org/10.24835/1607-0763-2020-2-119-130
Abstract
Aim: to explore functional connectivity of the normal brain during Stroop test modification and new suggested counting test performance.
Materials and methods. Data were acquired from 18 healthy volunteers who underwent fMRI examination on 3T scanner with Stroop test modification and new suggested counting test used as block paradigms.
Results. Functional connectivity analysis showed involvement of similar regions but with different distribution of positive correlations between them: interhemispheric significant positive correlations during Stroop test modification performance were found between anterior insular cortex, interhemispheric significant positive correlations during counting test performance were found between dorsolateral prefrontal cortices bilaterally and inferior parietal cortices bilaterally. Different distribution of significant correlations could be due to specificity of tasks. Comparative analysis showed significantly higher positive correlations with occipital cortex during Stroop test performance.
Conclusions. Received data allow alternative use of the abovementioned paradigms for executive functions investigation, with preference for counting test paradigm in patients with vision disturbances.
About the Authors
S, N. Morozova
Federal State Budgetary Scientific Institution “Research Center of Neurology”
Russian Federation
Russian Federation
Sofya N. Morozova – Cand. of Sci. (Med.), research fellow in radiology department
80, Volokolamskoye Shosse, 125367, Moscow
E. I. Kremneva
Federal State Budgetary Scientific Institution “Research Center of Neurology”
Russian Federation
Russian Federation
Elena I. Kremneva – Cand. of Sci. (Med.), major research fellow in radiology department
80, Volokolamskoye Shosse, 125367, Moscow
Z. Sh. Gadzhieva
Federal State Budgetary Scientific Institution “Research Center of Neurology”
Russian Federation
Russian Federation
Zukhra Sh. Gadzhieva – Cand. of Sci. (Med.), neurologist of 3rd neurological department
80, Volokolamskoye Shosse, 125367, Moscow
B. M. Akhmetzyanov
PET-Technology
Russian Federation
Russian Federation
Bulat M. Akhmetzyanov – Cand. of Sci. (Med.), radiologist
58-2, Richard Sorge str., 450054, Ufa
M. V. Krotenkova
Federal State Budgetary Scientific Institution “Research Center of Neurology”
Russian Federation
Russian Federation
Marina V. Krotenkova – Doct. of Sci. (Med.), head of the radiology department
80, Volokolamskoye Shosse, 125367, Moscow
L. A. Dobrynina
Federal State Budgetary Scientific Institution “Research Center of Neurology”
Russian Federation
Russian Federation
Larisa A. Dobrynina – Doct. of Sci. (Med.), head of the 3rd neurological department
80, Volokolamskoye Shosse, 125367, Moscow
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Morozova S.N., Kremneva E.I., Gadzhieva Z.Sh., Akhmetzyanov B.M., Krotenkova M.V., Dobrynina L.A. Evaluation of fMRI counting task efficiency for normal brain functional connectivity analisys during executive function examination. Medical Visualization. 2020;24(2):119-130. (In Russ.) https://doi.org/10.24835/1607-0763-2020-2-119-130
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