Биохимические основы визуализации при позитронной эмиссионной томографии в онкологии. Часть 1

Настоящая статья содержит обзор основных литературных данных, посвященных биохимическим основам клинического применения позитронной эмиссионной томографии - одной из наиболее перспективных технологий лучевой визуализации в онкологии. В первой части рассмотрены особенности биокинетики метаболических радиофармацевтических препаратов, таких как 18F-фтордезоксиглюкоза, радиомеченые маркеры липидного обмена 11С- и 18F-холин, 11C-ацетат, а также аналоги аминокислот 18F-дигидроксифенилаланин, 11C метионин, 18F-фторэтилтирозин, 11C-триптофан, 18F-флуцикловин. Кратко представлены результаты исследований, посвященных оценке эффективности, основные показания к применению, а также перспективные научные разработки в данной отрасли.

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