Proton 3D MR spectroscopy in the diagnosis of glial brain tumors
https://doi.org/10.24835/1607-0763-2019-3-8-18
Abstract
The purpose of this study was an assessment of the proton 3D MR spectroscopy efficacy in diagnosis of primary glial brain tumors.
Material and methods. Sixty three patients aged from 20 to 60 years with primary glial brain tumors of varying degrees of malignancy were examined. The ratios of main metabolites indices were evaluated with following comparison with the metabolites obtained in gray and white matter of the opposite hemisphere.
The ratios of main metabolites: Cho/Cr, NAA/Cr, Cho/NAA showed significant (p <0.005) differences in the groups of patients with low and high grade gliomas.
Results. The obtained data proved the efficacy of the proton 3D MR-spectroscopy in predicting of the glial brain tumors malignancy.
About the Authors
A. N. Tyurina
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Junior Researcher
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
Phone: +7-916-634-25-22
I. N. Pronin
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Academician of the Russian Academy of Sciences, doct. of med. sci., Professor
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
L. M. Fadeeva
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Medical Physicist
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
A. I. Batalov
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Junior Researcher
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
N. E. Zakharova
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
doct. of med. sci., Professor of Russian Academy of Sciences
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
A. E. Podoprigora
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
cand. of med. sci.
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
E. I. Shults
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
cand. of med. sci
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
V. N. Kornienko
Federal State Autonomous Institution “N.N. Burdenko National Medical Research Center of Neurosurgery” of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Academician of the Russian Academy of Sciences, doct. of med. sci., Professor
4-ya Tverskaya-Yamskaya str., 16, Moscow, Russia 125047
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Review
For citations:
Tyurina A.N., Pronin I.N., Fadeeva L.M., Batalov A.I., Zakharova N.E., Podoprigora A.E., Shults E.I., Kornienko V.N. Proton 3D MR spectroscopy in the diagnosis of glial brain tumors. Medical Visualization. 2019;(3):8-18. (In Russ.) https://doi.org/10.24835/1607-0763-2019-3-8-18
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