New technologies in breast cancer detection – contrast enhanced dual-energy spectral mammography
https://doi.org/10.24835/1607-0763-2019-2-49-61
Abstract
Purpose: to study the possibilities of contrast enhanced dual-energy spectral mammography (CESM) in the diagnostics of malignant tumors in the breast.
Material and methods. Forty-seven patients with suspicious for breast cancer (BC) lesions underwent CESM. Digital mammography (MMG) and post-contrast images were correlated with the results of path morphological studies after surgery or puncture biopsy was performed.
Results. Sensitivity, specificity and overall accuracy in the diagnostics of breast cancer were 83.3%, 85.7%, 85.1% for digital mammography and 91.6%, 91.4%, 91.4% for CESM, respectively. The positive predictive value was 66.6% for digital MMG and 78.5% for CESM. The negative predictive value (NPV) was 96.9% for the CESM and exceeded NPV of the digital MMG, which was 93.7%.
Conclusion. Thus, these findings suggest that CESM is an effective method for the diagnostics of malignant tumors in the breast.
About the Authors
A. V. Chernaya
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia
Russian Federation
Russian Federation
Antonina V. Chernaya – cand. of med. sci., radiologist at the Department of Radiology
197758 Russian Federation, St. Petersburg, Pesochny, Leningradskaya str., 68. Phone: +7-921-744-19-20
S. N. Novikov
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia
Russian Federation
Sergey N. Novikov – doct. of med. sci., Head of the Radiotherapy Department, Leading researcher
Russian Federation
Sergey N. Novikov – doct. of med. sci., Head of the Radiotherapy Department, Leading researcher
P. V. Krivorotko
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia; I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Petr V. Krivorotko – doct. of med. sci., Head of the surgical department of breast tumors, Leading researcher
Russian Federation
Petr V. Krivorotko – doct. of med. sci., Head of the surgical department of breast tumors, Leading researcher
R. Kh. Ulyanova
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia
Russian Federation
Roksana Kh. Ulyanova – resident at the Department of Radiology
Russian Federation
Roksana Kh. Ulyanova – resident at the Department of Radiology
V. V. Danilov
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia
Russian Federation
Vsevolod V. Danilov – resident at the Department of Radiology
Russian Federation
Vsevolod V. Danilov – resident at the Department of Radiology
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Review
For citations:
Chernaya A.V., Novikov S.N., Krivorotko P.V., Ulyanova R.Kh., Danilov V.V. New technologies in breast cancer detection – contrast enhanced dual-energy spectral mammography. Medical Visualization. 2019;(2):49-61. (In Russ.) https://doi.org/10.24835/1607-0763-2019-2-49-61
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