Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
https://doi.org/10.24835/1607-0763-2019-1-112-117
Abstract
The development of secondary tumors is a rare but well-known late effect of radiation therapy of lesions of the central nervous system. At the same time, malignant gliomas most often occur.
This article presents a rare clinical case of secondary anaplastic astrocytoma in a child who received chemoradia-tion therapy for medulloblastoma after surgical treatment.
Purpose. Demonstration of a rare occurrence of anaplastic astrocytoma after surgical and chemoradiation treatment of medulloblastoma.
About the Authors
N. V. Nudnov
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Nikolay V. Nudnov - doct. of med. sci., Professor.
117997 Moscow, Profsoyuznaya str., 86, Phone: +7-985-224-04-68
Competing Interests: No conflict of interest
O. G. Zheludkova
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Olga G. Zheludkova - doct. of med. sci., Professor.
Moscow
Competing Interests: No conflict of interest
I. V. Mnatsakanova
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Irina V. Mnatsakanova - a clinical resident on the specialty in radiology.
Moscow
Competing Interests: No conflict of interest
T. V. Podoksenova
Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation
Russian Federation
Competing Interests: No conflict of interest
Russian Federation
Tatiana V. Podoksenova - a clinical resident on the specialty in oncology.
Moscow
Competing Interests: No conflict of interest
References
1. You S.H., Lyu C.J., Kim D.S., Suh C.O. Second primary brain tumors following cranial irradiation for pediatric solid brain tumors. Child's Nerv. Syst. 2013; 29: 1865-1870. https://doi.org/10.1007/s00381-013-2098-4.
2. Kleriga E., Sher J.H., Nallainathan S.K., Stein S.C., Sacher M. Development of cerebellar malignant astrocytoma at site of a medulloblastoma treated 11 years earlier. Case Rep. J. Neurosurg. 1978; 49: 445-449. https://doi.org/10.3171/jns.1978.49.3.0445.
3. Paulino A.C., Mai W.Y., Chintagumpala M., Taher A., Teh B.S. Radiation-induced malignant gliomas: is there a role for reirradiation? Int. J. Radiat. Oncol. Biol. Phys. 2008; 71: 1381-1387. https://doi.org/10.1016/j.ijrobp.2007.12.018.
4. Louis D.N., Ohgaki H., Wiestler O.D., Cavenee W.K., Burger P.C., Jouvet A., Scheithauer B.W., Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007; 114 (2): 97-109. https://doi.org/10.1007/s00401-007-0243-4.
5. Ostrom Q.T, Gittleman H., Liao P., Rouse C., Chen Y., Dowling J., Wolinsky Y., Kruchko C., Barnholtz-Sloan J. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014; 4 (16, Suppl.): iv1-iv63. https://doi.org/10.1093/neuonc/nou223.
6. Prados M.D., Gutin P.H., Phillips T.L., Wara W.M., Larson D.A., Sneed P.K., Davis R.L., Ahn D.K., Lamborn K., Wilson C.B. Highly anaplastic astrocytoma: a review of 357 patients treated between 1977 and 1989. Int. J. Radiat. Oncol. Biol. Phys. 1992; 23 (1): 3-8.
7. Kornienko V.N., Pronin I.N. Diagnostic Neuroradiology. Vol. II: Brain Tumors. Moscow, 2009; 27-31. (In Russian)
8. Mechtler L. Neuroimaging in neuro-oncology. Neurol. Clin. 2009; 27 (1): 171-201. https://doi.org/10.1016/j.ncl.2008.09.015.
9. Henson J.W., Gaviani P., Gonzalez R.G. MRI in treatment of adult gliomas. Lancet Oncol. 2005; 6 (3): 167-175. https://doi.org/10.1016/S1470-2045(05)01767-5.
10. Hutterer M., Nowosielski M., Putzer D., Jansen N.L., Seiz M., Schocke M., McCoy M., Gobel G., la Fougere C., Virgolini I.J., Trinka E., Jacobs A.H., Stockhammer G. [18F]-fluoro-ethyl-L-tyrosine PET: a valuable diagnostic tool in neuro-oncology, but not all that glitters is glioma. Neuro Oncol. 2013; 15 (3): 341-351. https://doi.org/10.1093/neuonc/nos300.
Review
For citations:
Nudnov N.V., Zheludkova O.G., Mnatsakanova I.V., Podoksenova T.V. Russian Scientific Center of Roentgenoradiology of the Ministry of Healthcare of the Russian Federation. Medical Visualization. 2019;(1):112-117. (In Russ.) https://doi.org/10.24835/1607-0763-2019-1-112-117
Views:
981
Email this article 