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COMPARISON OF COMPUTED TOMOGRAPHY WITH INTRAVASCULAR ULTRASOUND IN EVALUATION OF CORONARY PLAQUES PARAMETERS

https://doi.org/10.24835/1607-0763-2018-4-7-19

Abstract

Purpose. To determine the possibilities of coronary CT-angiography (CTA) in evaluation of qualitative and qualitative parameters of coronary plaques in comparison with intravascular ultrasound (IVUS).


Matherials and methods. 37 patients (29 men, 8 women) with symptoms of acute coronary syndrome (ACS) were included in the study. Unstable angina was detected in 24 patients, acute myocardial infarction (AMI) – in 13 patients. Averageage was 58 [44; 65] years. CTA had been performed as the first method of beam diagnostics in all cases if it was not necessary to use the emergency selective coronary angiography (CAG). IVUS was performed in one, two or three coronary arteries of every patient. Total, 60 coronary lesionsin 55 arteries were examined with IVUS. IVUS data was compared with CTA data.


Results. Methods well correlated in detection of plaque burden (r = 0.823; p < 0.0001), plaque length (r = 0.932, p < 0.0001), remodeling index(RI) (r = 0.906; p < 0.0001). Sensitivity and specificity of CTA in detection of irregular contour was 96.1% and 88.9% (area under ROC-curve 0.925), positive remodeling – 100% and 97.4% (area under ROC-curve 0.974). CTA and IVUS in evaluation of spotty calcinates was not coincide in 9 plaques, sensitivity and specificity of CTA in detection of 71% and 100% (area under ROC-curve 0.855).
Discussion. Comparison of CTA and IVUS was performed in evaluation of plaques features in patients with ACS. This analysis showed high comparability of methods for evaluation of coronary stenosis degree, RI, plaque burden, length and contour. Thus, the characteristics of plaques according to CTA data can be used to stratify the risk of development of ACS.


Conclusion. CTA – fast non-invasive method of coronary plaques evaluation. CTA correlates well with IVUS.

About the Authors

M. A. Shariya
National Medical Research Center of Cardiology.
Russian Federation

Merab A. Shariya – doct. of med. sci., Professor, leading researcher at tomography department.

Moscow.



M. S. Shabanova
National Medical Research Center of Cardiology.
Russian Federation

Maria S. Shabanova – research assistant at tomography department.

Moscow.


T. N. Veselova
National Medical Research Center of Cardiology.
Russian Federation

Irina N. Merkulova – doct. of med. sci., senior researcher at emergency cardiology department.

Moscow.



I. N. Merkulova
National Medical Research Center of Cardiology.
Russian Federation

Tatyana N. Veselova – doct. of med. sci., Professor, senior researcher at tomography department.

Moscow.


V. M. Mironov
National Medical Research Center of Cardiology.
Russian Federation

Vsevolod M. Mironov – cand. of med. sci., cardiologist at department of interventional radiology.

Moscow.


S. A. Gaman
National Medical Research Center of Cardiology.
Russian Federation

Svetlana A. Gaman – cand. of med. sci., researcher of the tomography department.

Moscow.



S. K. Ternovoy
National Medical Research Center of Cardiology; Sechenov University.
Russian Federation

Sergey K. Ternovoy – academician of the RAS, doct. of med. sci., Professor, Head of the tomography department, Head of the Department of Imaging and Radiation Therapy.

Moscow.


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Review

For citations:


Shariya M.A., Shabanova M.S., Veselova T.N., Merkulova I.N., Mironov V.M., Gaman S.A., Ternovoy S.K. COMPARISON OF COMPUTED TOMOGRAPHY WITH INTRAVASCULAR ULTRASOUND IN EVALUATION OF CORONARY PLAQUES PARAMETERS. Medical Visualization. 2018;(4):7-19. (In Russ.) https://doi.org/10.24835/1607-0763-2018-4-7-19

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