Ground Glass Opacity: from observation to action. a modern diagnostic tool for peripheral focal ground glass opacity in the lungs

Aim: the article presents the results of the effectiveness of bronchoscopy with various options of bronchobiopsy under CT control in fluoroscopy mode with preliminary CT navigation in the diagnosis of peripheral foci in the lungs of the “ground glass” type.

To evaluate the capabilities of a combined technique of bronchoscopy with forceps and brush biopsies under CT control in fluoroscopy mode (SmartView Rx) with preliminary CT navigation (CTn+BS+CTf) in the diagnosis of peripheral lesions in the lungs of the "ground glass" type up to 3 cm in maximum dimension, in particular for the detection of stage 1 lung cancer.

Materials and methods. In a prospective study, the effectiveness of CT-guided bronchobiopsy in fluoroscopy mode with preliminary CT navigation was examined in 32 patients with newly detected ground-glass opacity lesions up to 3 cm in the lungs with suspected malignancy.

Results.This article presents the effectiveness of bronchoscopy with various CT-guided bronchobiopsy options using fluoroscopy and preliminary CT navigation in the diagnosis of peripheral ground-glass pulmonary lesions. The effectiveness of the procedure in the study group was 62.5% versus 21.1% in the control group (p = 0.006), an increase of +41.4%.

Conclusion. The use of CT navigation and CT fluoroscopy in bronchoscopy of peripheral ground-glass pulmonary lesions improves diagnostic efficiency and accuracy while reducing the invasiveness of the procedure. Bronchoscopy combined with CT navigation and CT fluoroscopy can be considered the method of choice for morphological verification of peripheral ground-glass pulmonary lesions.

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