Применение радиомики в диагностике рака шейки матки: систематический обзор

Цель исследования: проанализировать результаты изучения эффективности применения радиомического анализа при интерпретации лучевых изображений в уточнении диагностики рака шейки матки.

Материал и методы. Проведен систематический поиск медицинских статей в базах данных PubМed/MEDLINE, eLibrary, Scopus, в ресурсах NCCN, ESUR, ACR.

Результаты. При подборе медицинских статьей было выявлено в общей сложности 289 уникальных публикации, 218 из которых соответствовали критериям исключения. В итоговый обзор вошла 71 статья. Оценка средних точностных характеристик моделей производилась по значению площади под ROC-кривой (AUC), в том числе точность, чувствительность, специфичность и C-индекс.

Заключение. Рассмотрены основные ключевые аспекты и достоинства применения радиомики и текстурного анализа изображений при диагностике рака шейки матки. Внедрение радиомического анализа привело к обновленному восприятию анализа медицинских изображений. Результаты ряда исследований демонстрируют, что данные, извлекаемые с помощью радиомического анализа, обладают значительной диагностической и прогностической ценностью, позволяя объективно оценивать характеристики опухоли, ее стадию и распространенность, проводить дифференциальную диагностику новообразований.

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