The role of X-ray navigation in transapical implantation of mitral neochords for significant mitral regurgitation on the beating heart
https://doi.org/10.24835/1607-0763-1546
Abstract
Introduction. X-ray navigation in modern cardiac surgery is a revolutionary technology that allows to increase the accuracy and safety of cardiac surgeries significantly. Currently, navigation under direct X-ray control in surgeries to restore the mitral valve chords is used only when implanting chords using the ChordArt method. In addition, X-ray navigation and external implantation of the mitral neochord are used in such methods of mitral regurgitation correction as MitraClip and transcatheter mitral valve replacement (TMVR).
The objective. To systematically review the scientific evidence on the use of radiographic navigation in mitral valve interventions in case of significant mitral regurgitation. To identify radiographic projections that allow the most accurate visualization of cardiac structures required for neochords implantation.
Materials and methods. An analysis of studies devoted to the use of X-ray navigation in transapical implantation of mitral neochords for significant mitral regurgitation on the beating heart was performed. The search was performed in the PubMed and Elibrary databases from 2009 to 2024 using the following keywords: “mitral valve”, “mitral regurgitation”, “X-ray navigation”, “cardiovascular surgery”, “transapical chord repair”, “transcatheter interventions”, “coronary sinus”, “circumflex artery”, “MitraClip”, “TMVR – Transcatheter Mitral Valve Repair” using AND, OR operators.
Results. A total of 257 articles were analyzed, 65 of which were used to compile the review. The analysis revealed that the main method of visualizing instruments in the heart cavities during interventions on the mitral valve is intraoperative fluoroscopy. The most acceptable projections for performing surgery on transapical implantation of mitral neochords in case of significant mitral regurgitation on a beating heart were determined.
Conclusion. The results of the conducted analysis showed that X-ray navigation is an integral method of intraoperative navigation, which should be used during transapical implantation of mitral neochords in case of significant mitral regurgitation on a beating heart.
About the Authors
G. G. KhubulavaRussian Federation
Gennady G. Khubulava – Russian Academy of Sciences (RAS) Full Member, Doct. of Sci. (Med.), Professor, Head of the Department of Faculty Surgery, Head of the Scientific and Clinical Center for Cardiovascular Surgery at the Research Institute of Surgery and Emergency Medicine, Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation, Saint Petersburg
https://orcid.org/0000-0002-9242-9941
E. V. Bystrov
Russian Federation
Eduard V. Bystrov – 6th-year student of the Faculty of Medicine, Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation, Saint Petersburg
https://orcid.org/0009-0003-4425-1186
N. S. Titov
Nikita S. Titov – clinical resident of the Department of Faculty Surgery, Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation, Saint Petersburg
https://orcid.org/0000-0002-6302-0776
N. S. Bunenkov
Nikolai S. Bunenkov – Cand. of Sci. (Med.), surgeon, Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation, Saint Petersburg
https://orcid.org/0000-0003-4331-028X
V. V. Komok
Vladimir V. Komok – Cand. of Sci. (Med.), Cardiovascular surgeon at the Research Institute of Surgery and Emergency Medicine, Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation, Saint Petersburg
https://orcid.org/0000-0002-3834-7566
A. S. Nemkov
Alexander S. Nemkov – Doct. of Sci. (Med.), Professor of the Department of Faculty Surgery, cardiovascular surgeon, Pavlov First Saint Petersburg State Medical University of the Ministry of Healthcare of Russian Federation, Saint Petersburg
https://orcid.org/0000-0002-5152-0001
References
1. Domenech B., Pomar J. L., Prat-González S. et al. Valvular Heart Disease Epidemics. J. Heart Valve Dis. 2016; 25 (1): 1–7. https:// doi.org/10.3390/medsci10020032
2. Sengupta A., Alexis S.L., Zaid S. et al. Imaging the mitral valve: a primer for the interventional surgeon. Ann. Cardiothorac. Surg. 2021; 10 (1): 28–42. http://doi.org/10.21037/acs-2020-mv-16
3. Gheorghe L.L., Mobasseri S., Agricola E. et al. Imaging for Native Mitral Valve Surgical and Transcatheter Interventions. JACC Cardiovasc. Imaging. 2021; 14 (1): 112–127. https://doi.org/10.1016/j.jcmg.2020.11.021
4. Zhang T., Dou Y., Luo R. et al. A review of the development of interventional devices for mitral valve repair with the implantation of artificial chords. Front. Bioeng. Biotechnol. 2023; 1–17. http://doi.org/10.3389/fbioe.2023.1173413
5. Tabata N., Sugiura A., Tsujita K. et al. Percutaneous interventions for mitral and tricuspid heart valve diseases. Cardiovasc. Interv. Ther. 2020; 35 (1): 62–71. https://doi.org/10.1007/s12928-019-00610-z
6. Colli A., Zucchetta F., Torregrossa G. et al. Transapical off-pump mitral valve repair with Neochord Implantation (TOP-MINI): step-by-step guide. Ann. Cardiothorac. Surg. 2015; 4 (3): 295–297. https://doi.org/10.3978/j.issn.2225-319X.2015.05.01
7. Colli A., Adams D., Fiocco A. et al. ransapical NeoChord mitral valve repair. Ann. Cardiothorac. Surg. 2018; 7 (6): 812–820. http://doi.org/10.21037/acs.2018.11.04
8. Wunderlich N.C., Beigel R., Ho S.Y. et al. Imaging for Mitral Interventions: Methods and Efficacy. JACC Cardiovasc. Imaging. 2018; 11 (6): 872–901. https://doi.org/10.1016/j.jcmg.2018.02.024
9. Fiocco A., Nadali M., Speziali G. et al. Transcatheter Mitral Valve Chordal Repair: Current Indications and Future Perspectives. Front. Cardiovasc. Med. 2019; 6: 1–10. https://doi.org/10.3389/fcvm.2019.00128
10. Faletra F.F., Pozzoli A., Agricola E. et al. Echocardiographic-fluoroscopic fusion imaging for transcatheter mitral valve repair guidance. Eur. Heart J. Cardiovasc. Imaging. 2018; 19 (7): 715–726. https://doi.org/10.1093/ehjci/jey067
11. Spaziano M., Thériault-Lauzier P., Meti N. et al. Optimal fluoroscopic viewing angles of left-sided heart structures in patients with aortic stenosis and mitral regurgitation based on multislice computed tomography. J. Cardiovasc. Comput. Tomogr. 2016; 10 (2): 162–172. https://doi.org/10.1016/j.jcct.2015.12.007
12. Blanke P., Naoum C., Webb J. et al. Multimodality Imaging in the Context of Transcatheter Mitral Valve Replacement: Establishing Consensus Among Modalities and Disciplines. JACC Cardiovasc. Imaging. 2015; 8 (10): 1191–1208. https://doi.org/10.1016/j.jcmg.2015.08.004
13. Biaggi P., Fernandez-Golfín C., Hahn R. et al. Hybrid Imaging During Transcatheter Structural Heart Interventions. Curr. Cardiovasc. Imaging Rep. 2015; 8 (33): 1–14. https://doi.org/10.1007/s12410-015-9349-6
14. Faletra F.F., Pedrazzini G., Pasotti E. et al. Side-by-side comparison of fluoroscopy, 2D and 3D TEE during percutaneous edge-to-edge mitral valve repair. JACC Cardiovasc. Imaging. 2012; 5 (6): 656–661. https://doi.org/10.1016/j.jcmg.2012.02.014
15. Thériault-Lauzier P., Andalib A., Martucci G. et al. Fluoroscopic anatomy of left-sided heart structures for transcatheter interventions: insight from multislice computed tomography. JACC Cardiovasc. Interv. 2014; 7 (9): 947–957. https://doi.org/10.1016/j.jcin.2014.06.002
16. Blanke P., Dvir D., Naoum C. et al. Prediction of fluoroscopic angulation and coronary sinus location by CT in the context of transcatheter mitral valve implantation. J. Cardiovasc. Comput. Tomogr. 2015; 9 (3): 183–192. https://doi.org/10.1016/j.jcct.2015.02.007
17. del Valle-Fernández R., Jelnin V., Panagopoulos G. et al. Insight into the dynamics of the coronary sinus/great cardiac vein and the mitral annulus: implications for percutaneous mitral annuloplasty techniques. Circ. Cardiovasc. Interv. 2009; 2 (6): 557–564. https://doi.org/10.1161/CIRCINTERVENTIONS.109.873281
18. Rottländer D., Saal M., Ögütcü A. et al. Anatomy and Topography of Coronary Sinus and Mitral Valve Annulus in Functional Mitral Regurgitation. Front. Cardiovasc. Med. 2022; 22 (9): 1–10. https://doi.org/10.3389/fcvm.2022.868562
19. Gutleben K.J., Nölker G., Ritscher G. et al. hree-dimensional coronary sinus reconstruction-guided left ventricular lead implantation based on intraprocedural rotational angiography: a novel imaging modality in cardiac resynchronization device implantation. Europace. 2011; 13 (5): 675–682. https://doi.org/10.1093/europace/eur004
20. Duckett S.G., Ginks M.R., Knowles B.R. et al. Advanced image fusion to overlay coronary sinus anatomy with real-time fluoroscopy to facilitate left ventricular lead implantation in CRT. Pacing Clin. Electrophysiol. 2011; 34 (2): 226–234. https://doi.org/10.1111/j.1540-8159.2010.02940.x
21. Empen K., Kuon E., Hummel A. et al. Comparison of rotational with conventional coronary angiography. Am. Heart J. 2010; 160 (3): 552–563. https://doi.org/10.1016/j.ahj.2010.06.011
22. Kočka V., Thériault-Lauzier P., Xiong T.Y. et al. Optimal Fluoroscopic Projections of Coronary Ostia and Bifurcations Defined by Computed Tomographic Coronary Angiography. JACC Cardiovasc. Interv. 2020; 13 (21): 2560–2570. https://doi.org/10.1016/j.jcin.2020.06.042
23. Garcia J.A., Movassaghi B., Casserly I.P. et al. Determination of optimal viewing regions for X-ray coronary angiography based on a quantitative analysis of 3D reconstructed models. Int. J. Cardiovasc. Imaging. 2009; 25 (5): 455–462. https://doi.org/10.1007/s10554-008-9402-5
24. Endovascular surgery: National guideline: Four-Volume Edition. Vol. 2: Ischemic heart disease / Ed. B.G. Alekyan. M.: Littera, 2017. 792 p. (In Russian)
25. Torres C.S., Sanders J.V.S., Martins de Brito H. et al. Anatomical relationship between mitral valve annulus and circumflex artery and its surgical implications. Morphologie. 2020; 104 (346): 182–186. https://doi.org/10.1016/j.morpho.2020.03.003
26. Merculov E.V., Mironov V.M., Samko A.N. Coronary angiography, ventriculography, shuntography. In illustrations and schemes. M.: Media-Medica, 2011. 100 p. (In Russian)
Supplementary files
Review
For citations:
Khubulava G.G., Bystrov E.V., Titov N.S., Bunenkov N.S., Komok V.V., Nemkov A.S. The role of X-ray navigation in transapical implantation of mitral neochords for significant mitral regurgitation on the beating heart. Medical Visualization. (In Russ.) https://doi.org/10.24835/1607-0763-1546