Twinkling artifact in differential diagnosis of mammary calcinates
https://doi.org/10.24835/1607-0763-1025
Abstract
Research goal: evaluation of the possibility of using an ultrasound twinkling artifact in the detection of breast calcifications as a diagnostic criterion for breast cancer.
Material and methods. A targeted ultrasound study using color Doppler mapping was performed to determine the presence of a twinkling artifact in 112 patients who had calcifications detected during X-ray mammography.
Results. According to the ultrasound examination, the twinkling artifact was registered only in 10 of the 112 women examined. A pronounced twinkling artifact was registered in 3 patients, the calcifications were single, mainly lobular, with a size of more than 1 mm. In 5 cases, the flicker artifact was determined to be of moderate severity, and the distribution pattern was also dominated by single ones, more than 1 mm. Two patients with grouped calcinates had a weakly expressed twinkling artifact, their dimensions were also more than 1 mm.
Conclusion. The data obtained indicate that the Doppler twinkling artifact in the mammary glands occurs only in macrocalcinates (larger than 1 mm) and, mainly, single ones. Modern ultrasound devices do not allow registering a twinkling artifact in calcinates smaller than 1 mm, which indicates that it is impossible to use Doppler color coding to detect microcalcinates as a predictor of breast cancer.
About the Authors
A. I. Gromov
A.I. Evdokimov Moscow State University of Medicine and Dentistry; Clinical hospital No.2 of “Medsi group” Joint Stock Company
Russian Federation
Russian Federation
Alexander I. Gromov – Doct. of Sci. (Med.), Professor, Professor of Department of Radiology, Moscow State University of Medicine and Dentistry named after A.I. Evdokimov; Head of Radiology Department of Clinical hospital No.2 of “Medsi group” Joint Stock Company
6/3, 2nd Botkinski pr., Moscow, 125284
Phone: +7-495-737-61-82 (42021)
Yu. A. Komin
Obninsk Institute for Nuclear Power Engineering; Medical military facility
Russian Federation
Russian Federation
Yury A. Komin – Assistant of Department of Morphology of Obninsk Institute for Nuclear Power Engineering; doctor of military medical institution
1, Studgorodok, Obninsk 249039
Moscow
S. A. Mozerov
Obninsk Institute for Nuclear Power Engineering
Russian Federation
Russian Federation
Sergey A. Mozerov – Doct. of Sci. (Med.), Аssociate professor, Head of Department of Morphology
1, Studgorodok, Obninsk 249039
S. K. Krasnickaya
Medical military facility
Russian Federation
Russian Federation
Svetlana K. Krasnickaya – Head of department
Moscow
References
1. Korzhenkova G.P. Complex X-ray and sonographic diagnostics of breast diseases. Practical guide / Edited by N.V. Kochergina. N.N. Blokhin NMRCO. Moskow: Strom, 2004. 123 p. (In Russian)
2. Rahmouni A., Bargoin R., Herment A. Color Doppler twinkling artifact in hyperechoic regions. Radiology. 1996; 199: 269–271.
3. Vasiliev A. Yu., Gromov A. I. Color Doppler mapping using energy Doppler in the assessment of prostate pathology. Military Medical Journal. 1997; 318 (4): 33–37. (In Russian)
4. Kulberg N.S., Gromov A.I., Leonov D.V., Osipov L.V., Usanov M.S., Morozov S.P. Ultrasound diagnostic mode for kidney stone and soft tissue calculi detection. Radiology-practice. 2018; 1: 37–49.
5. Leonov D.V., Kulberg N.S., Gromov A., Vladzimirsky A.V., Morozov S.P. Discovery of two types of twinkling can explain contradictory observations among twinkling artifact investigators in ultrasound imaging. https://arxiv.org № 1912.02490, 2019. 36 p.
6. Fazylov A. A., Fazylova S. A. Breast cancer: the contribution of the echographic “Gromov–Zykin effect” to the clarifying diagnosis. IV Congress of the Russian Association of Ultrasound Diagnostics Specialists in Medicine. Abstracts of reports. Moscow, 2003: 223. (In Russian)
7. Fujimoto Y., Shimono C., Shimoyama N., Osaki M. Twinkling Artifact of Microcalcifications in Breast Ultrasound. Ultrasound Med. Biol. 2017; 43: 21.
8. Relea A., Alonso J.A., González M., Zornoza C., Bahamonde S., Vinuela B.E., Encinas M.B. Usefulness of the twinkling artifact on Doppler ultrasound for the detection of breast microcalcifications. Radiología. 2018; 60 (5): 413–423.
Review
For citations:
Gromov A.I., Komin Yu.A., Mozerov S.A., Krasnickaya S.K. Twinkling artifact in differential diagnosis of mammary calcinates. Medical Visualization. 2021;25(3):157-166. (In Russ.) https://doi.org/10.24835/1607-0763-1025
Views:
1554
Email this article 