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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medvis-85</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МАЛЫЙ ТАЗ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SMALL PELVIS</subject></subj-group></article-categories><title-group><article-title>Особенности МР-семиотики различных гистологических типов лейомиом матки при планировании эмболизации маточных артерий</article-title><trans-title-group xml:lang="en"><trans-title>MRI in Differentiating Leiomyoma Types in Women Undergoing Uterine Artery Embolization</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павловская</surname><given-names>Евгения Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlovskaya</surname><given-names>Evgenia Aleksandrovna</given-names></name></name-alternatives><email xlink:type="simple">e.a.pavlovskaya@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юхно</surname><given-names>Елена Антоновна</given-names></name><name name-style="western" xml:lang="en"><surname>Yukhno</surname><given-names>Elena Antonovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Труфанов</surname><given-names>Геннадий Евгеньевич</given-names></name><name name-style="western" xml:lang="en"><surname>Trufanov</surname><given-names>Gennadiy Evgenyevich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рязанов</surname><given-names>Владимир Викторович</given-names></name><name name-style="western" xml:lang="en"><surname>Ryazanov</surname><given-names>Vladimir Viktorovich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сосин</surname><given-names>Сергей Андреевич</given-names></name><name name-style="western" xml:lang="en"><surname>Sosin</surname><given-names>Sergey Andreevich</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБВОУ ВПО “Военно-медицинская академия им. С.М. Кирова” МО РФ<country>Россия</country></aff><aff xml:lang="en">S.M. Kirov Millitary Medical Academy<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГБВОУ ВПО “Военно-медицинская академия им. С.М. Кирова” МО РФ; ФГБУ “Федеральный медицинский исследовательский центр им. В.А. Алмазова”<country>Россия</country></aff><aff xml:lang="en">S.M. Kirov Millitary Medical Academy; Federal V.A. Almazov Medical Research Centre<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ФГБУ “Федеральный медицинский исследовательский центр им. В.А. Алмазова”<country>Россия</country></aff><aff xml:lang="en">Federal V.A. Almazov Medical Research Centre<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2014</year></pub-date><volume>0</volume><issue>4</issue><fpage>90</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Павловская Е.А., Юхно Е.А., Труфанов Г.Е., Рязанов В.В., Сосин С.А., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Павловская Е.А., Юхно Е.А., Труфанов Г.Е., Рязанов В.В., Сосин С.А.</copyright-holder><copyright-holder xml:lang="en">Pavlovskaya E.A., Yukhno E.A., Trufanov G.E., Ryazanov V.V., Sosin S.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.vidar.ru/jour/article/view/85">https://medvis.vidar.ru/jour/article/view/85</self-uri><abstract><p>Цель исследования: оценить эффективность эмболизации маточных артерий (ЭМА) по данным МРТ в зависимости от положения, структуры лейомиом, а также наличия сопутствующего эндометриоза. Материал и методы. На томографе с индукцией магнитного поля 1,5 Тл была проведена МРТ малого таза 20 женщинам с лейомиомами матки (107 лейомиом) в возрасте 41-46 лет. Перед проведением ЭМА МРТ выполнена всем 20 пациенткам, исследование повторяли через 1 мес после вмешательства, также исследование было проведено через 6 мес у 8 пациенток, через 1 год после вмешательства - у 4. Результаты. Субмукозные лейомиомы наблюдались в 25% случаев, интрамуральные - в 32%, субсерозные - в 30,7%. Наиболее часто отмечался гиалиновый тип дегенерации лейомиом - 44%, лейомиомы типичного строения без признаков дегенерации наблюдались в 36% случаев. В большей степени отмечалось уменьшение лейомиом клеточного типа (до 50% через 1 мес, 64% через 6 мес и до 75% от исходного объема за 12 мес после ЭМА). Уменьшение лейомиоматозных узлов с признаками гиалиновой, кистозной и миксоидной дегенерации наблюдалось реже (в среднем до 44, 50 и 65% соответственно). Выводы. МРТ позволяет провести тщательный анализ положения, МР-структуры и кровоснабжения лейомиоматозных узлов при планировании ЭМА, определить точные размеры узлов для оценки их уменьшения в динамике. На эффективность ЭМА влияют наличие сопутствующего эндометриоза, а также тип строения лейомиоматозного узла.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to evaluate the efficiency of uterine artery embolization (UAE) by means of MRI, depending on their location, structure type and the presence of accompanying endometriosis Methods and materials. MRI (1.5 T) was performed in 20 women with leiomyomas (107 nodes) at the age of 41-46 years, presented for consideration for UAE before and 1 month after the manipulation. MRI was also performed in 6 months after the UAE in 8 women and in 12 months in 4 women. Results. Submucosal nodes were determined in 25% of cases, intramural - in 32% and subserosal - in 30.7%. Hyalinization of the nodes was noted in 44% of cases, the second most frequent type was node without signs of degeneration - 36%. The most prominent dynamics was noted in cellular leiomyoma type - the volume decrease was up to 50% in one month, 64% in 6 months and 75% in 12 months after UAE. In leiomyomas with hyaline, cystic or myxoid type of degeneration volume shrinkage was less prominent - 44%, 50% and 65% accordingly. Conclusion. MRI can provide us with precise information about location, size, structure and vascularization of leiomyomas before and after UAE. UAE efficiency depends on accompanying endometriosis and node structure.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитно-резонансная томография</kwd><kwd>контрастное усиление</kwd><kwd>миома матки</kwd><kwd>эмболизация маточных артерий</kwd><kwd>эндометриоз</kwd><kwd>contrast-enhanced magnetic resonance imaging</kwd><kwd>leiomyoma uteri</kwd><kwd>uterine artery embolization</kwd><kwd>endometriosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hillard P.J.A. Benign diseases of the female reproductive tract: symptoms and signs. Novak’s gynecology, 13th ed. By Berek J. Philadelphia: Lippincott Williams &amp; Wilkins, 2002. 1200 p.</mixed-citation><mixed-citation xml:lang="en">Hillard P.J.A. Benign diseases of the female reproductive tract: symptoms and signs. Novak’s gynecology, 13th ed. By Berek J. Philadelphia: Lippincott Williams &amp; Wilkins, 2002. 1200 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Kido A., Ascher S.M. Comparison of uterine peristalsis before and after uterine artery embolization at 3-T MRI. Am. J. Radiol. 2011; 196: 1431-1435.</mixed-citation><mixed-citation xml:lang="en">Kido A., Ascher S.M. Comparison of uterine peristalsis before and after uterine artery embolization at 3-T MRI. Am. J. Radiol. 2011; 196: 1431-1435.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Zimmermann A., Bernuit D., Gerlinger C. et al. Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women. BMC Women's Health. 2012; 12 (6): 3-14.</mixed-citation><mixed-citation xml:lang="en">Zimmermann A., Bernuit D., Gerlinger C. et al. Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women. BMC Women's Health. 2012; 12 (6): 3-14.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Вихляева Е.М. Руководство по диагностике и лечению больных лейомиомой матки. М.: МЕДпресс-информ, 2004. 400 c.</mixed-citation><mixed-citation xml:lang="en">Вихляева Е.М. Руководство по диагностике и лечению больных лейомиомой матки. М.: МЕДпресс-информ, 2004. 400 c.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Сидорова И.С., Унанян А.Л., Агеев М.Б. и др. Современное состояние вопроса о патогенезе, клинике, диагностике и лечении миомы матки у женщин репродуктивного возраста. Акуш., гинекол., репродукция. 2012; 6 (4): 22-28.</mixed-citation><mixed-citation xml:lang="en">Сидорова И.С., Унанян А.Л., Агеев М.Б. и др. Современное состояние вопроса о патогенезе, клинике, диагностике и лечении миомы матки у женщин репродуктивного возраста. Акуш., гинекол., репродукция. 2012; 6 (4): 22-28.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Даниленко В.И., Малахов Р.М., Ягубов А.С. и др. Морфология лейомиомы матки. Акуш. и гинекол. 2005; 67(3): 29-31.</mixed-citation><mixed-citation xml:lang="en">Даниленко В.И., Малахов Р.М., Ягубов А.С. и др. Морфология лейомиомы матки. Акуш. и гинекол. 2005; 67(3): 29-31.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ланчинский В.И., Ищенко А.И. Современные представления об этиологии и патогенезе миомы матки. Вопр. гинекол., акуш. и перинатол. 2003; 2 (5-6): 64-69.</mixed-citation><mixed-citation xml:lang="en">Ланчинский В.И., Ищенко А.И. Современные представления об этиологии и патогенезе миомы матки. Вопр. гинекол., акуш. и перинатол. 2003; 2 (5-6): 64-69.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Davis K.M., Schlaff W.D. Medical management of uterine fibromyoma. Obstet. Gynecol. Clin. N. Am. 1995; 22: 637-657.</mixed-citation><mixed-citation xml:lang="en">Davis K.M., Schlaff W.D. Medical management of uterine fibromyoma. Obstet. Gynecol. Clin. N. Am. 1995; 22: 637-657.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Novak E.R., Woodruff J.D. Myoma and other benign tumors of the uterus: Gynecologic and obstetrics pathology. Philadelphia: W.B. Saunders Company, 1979. 795 p.</mixed-citation><mixed-citation xml:lang="en">Novak E.R., Woodruff J.D. Myoma and other benign tumors of the uterus: Gynecologic and obstetrics pathology. Philadelphia: W.B. Saunders Company, 1979. 795 p.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Muraze E., Siegelman E.S., Outwater E.K. et al. Uterine leiomyomas: hystopathologic features, MR imaging findings, differential diagnosis and treatment. Radiographics. 1999; 19: 1179-1197.</mixed-citation><mixed-citation xml:lang="en">Muraze E., Siegelman E.S., Outwater E.K. et al. Uterine leiomyomas: hystopathologic features, MR imaging findings, differential diagnosis and treatment. Radiographics. 1999; 19: 1179-1197.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rein M.S., Friedman A.J. Progesterone: critical role in the pathogenesis of uterine myomas. Am. J. Obstet. Gynecol. 1995; 172: 14-18.</mixed-citation><mixed-citation xml:lang="en">Rein M.S., Friedman A.J. Progesterone: critical role in the pathogenesis of uterine myomas. Am. J. Obstet. Gynecol. 1995; 172: 14-18.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Труфанов Г.Е., Панов В.О. Руководство по лучевой диагностике в гинекологии. СПб.: ЭЛБИ, 2008. 590 c.</mixed-citation><mixed-citation xml:lang="en">Труфанов Г.Е., Панов В.О. Руководство по лучевой диагностике в гинекологии. СПб.: ЭЛБИ, 2008. 590 c.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Сидорова И.С. Миома матки (современные проблемы этиологии, патогенеза, диагностики и лечения). М.: Медицинское информационное агентство, 2002. 254 c.</mixed-citation><mixed-citation xml:lang="en">Сидорова И.С. Миома матки (современные проблемы этиологии, патогенеза, диагностики и лечения). М.: Медицинское информационное агентство, 2002. 254 c.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Тихомиров А.М., Олейник Ч.Г., Лубнин Д.М. и др. Тактика лечения больных миомой матки: Методическое пособие для врачей акушеров-гинекологов. М.: Медицинское информационное агентство, 2007. 49 c.</mixed-citation><mixed-citation xml:lang="en">Тихомиров А.М., Олейник Ч.Г., Лубнин Д.М. и др. Тактика лечения больных миомой матки: Методическое пособие для врачей акушеров-гинекологов. М.: Медицинское информационное агентство, 2007. 49 c.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Reidy J.F., Bradley E.A. Uterine artery embolization for fibroid disease. Cardiovasc. Intervent. Radiol. 1998; 21: 357-360.</mixed-citation><mixed-citation xml:lang="en">Reidy J.F., Bradley E.A. Uterine artery embolization for fibroid disease. Cardiovasc. Intervent. Radiol. 1998; 21: 357-360.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Walker W.J., Pelage W.J. Uterine artery embolization for symptomatic fibroids: clinical results in 400 women with imaging follow-up. Br. J. Obstet. Gynecol. 2002; 109: 1262-1272.</mixed-citation><mixed-citation xml:lang="en">Walker W.J., Pelage W.J. Uterine artery embolization for symptomatic fibroids: clinical results in 400 women with imaging follow-up. Br. J. Obstet. Gynecol. 2002; 109: 1262-1272.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bulman J.C., Ascher S.M., Spies J.B. Current concepts in uterine fibroid embolization. Radiographics. 2012; 32 (6): 1735-1750.</mixed-citation><mixed-citation xml:lang="en">Bulman J.C., Ascher S.M., Spies J.B. Current concepts in uterine fibroid embolization. Radiographics. 2012; 32 (6): 1735-1750.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Wolanske K.A., Gordon R.L. Uterine artery embolization: where does it stand in the management of uterine leiomyomas? Pt 2. Appl. Radiol. 2004; 33 (10): 35-42.</mixed-citation><mixed-citation xml:lang="en">Wolanske K.A., Gordon R.L. Uterine artery embolization: where does it stand in the management of uterine leiomyomas? Pt 2. Appl. Radiol. 2004; 33 (10): 35-42.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Spies J.B. Uterine artery embolization for leiomyoma. Obstet. Gynecol. 2001; 98 (1): 29-34.</mixed-citation><mixed-citation xml:lang="en">Spies J.B. Uterine artery embolization for leiomyoma. Obstet. Gynecol. 2001; 98 (1): 29-34.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Moss J., Cooper K., Khaund A. et al. Randomized comparison of uterine artery embolization (UAE) with surgical treatment in patients with symptomatic uterine fibroids (REST trial): 5-year results. Br. J. Obstet. Gynecol. 2011; 118: 936-944.</mixed-citation><mixed-citation xml:lang="en">Moss J., Cooper K., Khaund A. et al. Randomized comparison of uterine artery embolization (UAE) with surgical treatment in patients with symptomatic uterine fibroids (REST trial): 5-year results. Br. J. Obstet. Gynecol. 2011; 118: 936-944.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Tomislav S., Maskovic J., Liana C.S. et al. Uterine artery embolization as nonsurgical treatment of uterine myomas. ISRN Obstet. Gynecol.2011; 31:4-10.</mixed-citation><mixed-citation xml:lang="en">Tomislav S., Maskovic J., Liana C.S. et al. Uterine artery embolization as nonsurgical treatment of uterine myomas. ISRN Obstet. Gynecol.2011; 31:4-10.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Hubert J. Imaging the female pelvis: when should MRI be considered? Appl. Radiol. 2008; 37 (1): 9-24.</mixed-citation><mixed-citation xml:lang="en">Hubert J. Imaging the female pelvis: when should MRI be considered? Appl. Radiol. 2008; 37 (1): 9-24.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Verma S.K., Bergin D., Gonsalves C.F. et al. Submucosal fibroids becoming endocavitary following uterine artery embolization: risk assessment by MRI. Am. J. Roentgenol. 2008; 190: 1220-1226.</mixed-citation><mixed-citation xml:lang="en">Verma S.K., Bergin D., Gonsalves C.F. et al. Submucosal fibroids becoming endocavitary following uterine artery embolization: risk assessment by MRI. Am. J. Roentgenol. 2008; 190: 1220-1226.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Siddiqui N., Nikolaidis P., Hammond N. Uterine artery embolization: pre- and post-procedural evaluation using magnetic resonance imaging. Abdom. Imaging. 2013; 38(5): 1161-1177.</mixed-citation><mixed-citation xml:lang="en">Siddiqui N., Nikolaidis P., Hammond N. Uterine artery embolization: pre- and post-procedural evaluation using magnetic resonance imaging. Abdom. Imaging. 2013; 38(5): 1161-1177.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
