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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medvis-25</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРЮШНАЯ ПОЛОСТЬ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMEN</subject></subj-group></article-categories><title-group><article-title>Диагностика метастатического поражения регионарных лимфатических узлов при раке желудка. Часть 2: Диагностическая эффективность компьютерной томографии при выявлении метастазов в регионарные лимфатические узлы у больных раком желудка</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of Lymph Node Status in Gastric Cancer. Part 2: Diagnostic Efficacy of Computed Tomography for the Detection of Lymph Node Metastases in Gastric Cancer Patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агабабян</surname><given-names>Татев Артаковна</given-names></name><name name-style="western" xml:lang="en"><surname>Agababian</surname><given-names>Tatev Artakovna</given-names></name></name-alternatives><email xlink:type="simple">tatevik.05@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Силантьева</surname><given-names>Наталья Константиновна</given-names></name><name name-style="western" xml:lang="en"><surname>Silanteva</surname><given-names>Natalya Konstantinovna</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ “Медицинский радиологический научный центр” Министерства здравоохранения России<country>Россия</country></aff><aff xml:lang="en">Medical Radiological Research Center of the Russian Ministry of Health<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2014</year></pub-date><volume>0</volume><issue>2</issue><fpage>61</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Агабабян Т.А., Силантьева Н.К., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Агабабян Т.А., Силантьева Н.К.</copyright-holder><copyright-holder xml:lang="en">Agababian T.A., Silanteva N.K.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.vidar.ru/jour/article/view/25">https://medvis.vidar.ru/jour/article/view/25</self-uri><abstract><p>Цель: изучить диагностическую эффективность КТ в выявлении метастазов в регионарные лимфатические узлы у больных раком желудка Материал и методы. Работа основана на клиникоморфологических сопоставлениях, выполненных у 69 больных раком желудка (42 (61%) мужчин, 27 (39%) женщин) в возрасте от 24 до 79 лет. На дооперационном этапе всем больным была выполнена МСКТ. КТ-диагностика состояния регионарных лимфатических узлов проведена по таким показателям, как наличие или отсутствие лимфатических узлов в зонах регионарного метастазирования, их количество, размеры, конфигурация. Статистическую обработку полученных данных проводили с использованием статистического пакета SPSS 13.0. Статистическую значимость различий между несвязанными группами оценивали по критерию х2 Пирсона, для оценки эффективности диагностических тестов выполняли анализ операционной характеристической кривой (ROC - Receiver Operating Characteristic curve). Результаты. Установлено, что возрастание числа регионарных лимфатических узлов, выявленных при КТ (3 и более), сопровождалось статистически достоверным увеличением частоты их метастатического поражения (х2 = 8,395; p = 0,004). Проведенный анализ показал статистически достоверную связь между размерами регионарных лимфатических узлов (до 10 мм или 10 мм и более), установленными при КТ-исследовании, и вероятностью их метастатического поражения (х2 = 8,448; p = 0,002). Выявление при КТ лимфатических узлов размерами 10 мм и более, форма которых округлая или приближается к ней (соотношение длинного и короткого диаметров узла &lt;1,5), с достоверностью свидетельствует о метастатическом поражении (х2 = 9,996; p = 0,001). Чувствительность КТ при диагностике метастатического поражения лимфатических узлов оказалось равной 86,4%, специфичность - 89,4%, точность - 88,4%, прогностичность положительного результата - 79,2% и прогностичность отрицательного результата - 93,3%. Выводы. Использование КТ-критериев метастатического поражения и КТ-схемы последовательной оценки регионарных лимфатических узлов повышает информативность предоперационной диагностики; позволяет врачу-рентгенологу последовательно изучить все возможные зоны локализации регионарных лимфатических узлов и выявить наличие или отсутствие измененных лимфатических узлов. Совокупность таких факторов, как локализация лимфатических узлов в зонах регионарного лимфооттока, количество лимфатических узлов более 3, размеры 10 мм и более, их округлая форма, с большой вероятностью свидетельствует о метастатическом характере поражения.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to determine the diagnostic efficacy of computed tomography (CT) in detecting of regional lymph nodes metastases in gastric cancer patients. Materials and methods. Work is based on the comparison of clinical and pathologic features in 69 gastric cancer patients (42 (61%) men, 27 (39%) women, ranging in age from 24 to 79 years). All of the patients underwent preoperative multidetector computed tomography (MDCT). Parameters of lymph nodes evaluated were presence or absence of nodes in the regional areas, their number, size and shape. Statistical analyses were performed with SPSS statistical software version 13.0. The qualitative data were evaluated with Pearson х2 test; the diagnostic values of lymph node shape for delectability of lymph node metastasis were evaluated by Receiver Operating Characteristic (ROC) analysis. Results. The frequency of lymph node metastasis was associated significantly with their number (three or more) (х2 = 8.395; p = 0.004), size (up to 10 mm or more than 10 mm) (х2 = 8.448; Р=0,002), and node shape (the ratio of long and short diameters &lt;1.5 site) (х2 = 9.996; Р = 0.001). Sensitivity of computed tomography in the assessment of metastatic lymph nodes were 86.4%, specificity - 89.4%, accuracy - 88.4%, positive predictive value - 79.2%, and its negative predictive value - 93.3%. Conclusion. The use of CT criteria and regional lymph node assessment scheme improves the preoperative evaluation and allows the radiologist to examine successively every possible zone of regional lymph nodes localization. Combination of factors such as: the location of lymph nodes, three or more nodes, and enlargement 10 mm or more, their rounded shape was the optimal diagnostic criterion for lymph node metastasis in patients with gastric cancer.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>регионарные лимфатические узлы</kwd><kwd>метастазы</kwd><kwd>компьютерная томография</kwd><kwd>gastric cancer</kwd><kwd>regional lymph nodes</kwd><kwd>metastases</kwd><kwd>computed tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dehn T.C., Rezneck R.H., Nockler I.B., White F.E. The preoperative assessment of advanced gastric cancer by computed tomography. Br. J. Surg. 1984; 71 (6): 413-417.</mixed-citation><mixed-citation xml:lang="en">Dehn T.C., Rezneck R.H., Nockler I.B., White F.E. The preoperative assessment of advanced gastric cancer by computed tomography. 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