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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medvis</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская визуализация</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Visualization</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0763</issn><issn pub-type="epub">2408-9516</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0763-1382</article-id><article-id custom-type="elpub" pub-id-type="custom">medvis-1382</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОСТИ И СУСТАВЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BONES AND JOINTS</subject></subj-group></article-categories><title-group><article-title>Современные методы визуализации подагрических тофусов</article-title><trans-title-group xml:lang="en"><trans-title>Modern methods of visualization of gouty tophi</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-9766-6986</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ким</surname><given-names>Тхе Ван</given-names></name><name name-style="western" xml:lang="en"><surname>Kim</surname><given-names>Tkhe Van</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ким Тхе Ван – аспирант кафедры лучевой диагностики и лучевой терапии ФГБОУ ВО СибГМУ Минздрава России, Томск. <ext-link xlink:href="https://orcid.org/0009-0002-9766-6986" ext-link-type="uri">https://orcid.org/0009-0002-9766-6986</ext-link>. E-mail: Pavel.kim.08@mail.ru</p></bio><bio xml:lang="en"><p>Postgraduate of the Radiology and Radiotherapy Department, Siberian State Medical University</p></bio><email xlink:type="simple">pavel.kim.08@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6231-7650</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Завадовская</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Zavadovskaya</surname><given-names>V. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Завадовская Вера Дмитриевна – доктор мед. наук, профессор, и.о. заведующей кафедрой лучевой диагностики и лучевой терапии ФГБОУ ВО СибГМУ Минздрава России, Томск. <ext-link xlink:href="https://orcid.org/0000-0001-6231-7650" ext-link-type="uri">https://orcid.org/0000-0001-6231-7650</ext-link>. E-mail: Wdzav@mail.ru</p></bio><bio xml:lang="en"><p>Vera D. Zavadovskaya – MD, Doct. of Sci. (Med.), Professor, Head of the Radiology and Radiotherapy Department, Siberian State Medical University, Tomsk. <ext-link xlink:href="https://orcid.org/0000-0001-6231-7650" ext-link-type="uri">https://orcid.org/0000-0001-6231-7650</ext-link>. E-mail: Wdzav@mail.ru </p></bio><email xlink:type="simple">Wdzav@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8812-4168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дегтярев</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Degtyarev</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дегтярев Илья Юрьевич – ассистент кафедры лучевой диагностики и лучевой терапии ФГБОУ ВО СибГМУ Минздрава России, Томск. <ext-link xlink:href="https://orcid.org/0000-0002-8812-4168" ext-link-type="uri">https://orcid.org/0000-0002-8812-4168</ext-link>. E-mail: ilya.degtyarev.4201@mail.ru</p></bio><bio xml:lang="en"><p>Ilia Yu. Degtyarev – Assistant of the Radiology and Radiotherapy Department, Siberian State Medical University, Tomsk. <ext-link xlink:href="https://orcid.org/0000-0002-8812-4168" ext-link-type="uri">https://orcid.org/0000-0002-8812-4168</ext-link>. E-mail: ilya.degtyarev.4201@mail.ru</p></bio><email xlink:type="simple">ilya.degtyarev.4201@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7582-3843</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Замышевская</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zamishevskaya</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Замышевская Мария Александровна – канд. мед. наук, ассистент кафедры лучевой диагностики и лучевой терапии ФГБОУ ВО СибГМУ Минздрава России, Томск. <ext-link xlink:href="https://orcid.org/0000-0001-7582-3843" ext-link-type="uri">https://orcid.org/0000-0001-7582-3843</ext-link>. E-mail: Zamyshevskayamari@mail.ru</p></bio><bio xml:lang="en"><p>Maria A. Zamyshevskaya – MD, Cand. of Sci. (Med.), Assistant of the Radiology and Radiotherapy Department, Siberian State Medical University, Tomsk. <ext-link xlink:href="https://orcid.org/0000-0001-7582-3843" ext-link-type="uri">https://orcid.org/0000-0001-7582-3843</ext-link>. E-mail: Zamyshevskayamari@mail.ru</p></bio><email xlink:type="simple">Zamyshevskayamari@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1321-7861</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Удодов</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Udodov</surname><given-names>V. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Удодов Владимир Дмитриевич – канд. мед. наук, ассистент кафедры лучевой диагностики и лучевой терапии ФГБОУ ВО СибГМУ Минздрава России, Томск. <ext-link xlink:href="https://orcid.org/0000-0002-1321-7861" ext-link-type="uri">https://orcid.org/0000-0002-1321-7861</ext-link>. E-mail: Udodov.vd@ssmu.ru </p></bio><bio xml:lang="en"><p>Vladimir D. Udodov – MD, Cand. of Sci. (Med.), Assistant of the Radiology and Radiotherapy Department, Siberian State Medical University, Tomsk. <ext-link xlink:href="https://orcid.org/0000-0002-1321-7861" ext-link-type="uri">https://orcid.org/0000-0002-1321-7861</ext-link>. E-mail: Udodov.vd@ssmu.ru</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0025-2147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зоркальцев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zorkalcev</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зоркальцев Максим Александрович – доктор мед. наук, доцент кафедры лучевой диагностики и лучевой терапии ФГБОУ ВО СибГМУ Минздрава России, Томск. <ext-link xlink:href="https://orcid.org/0000-0003-0025-2147" ext-link-type="uri">https://orcid.org/0000-0003-0025-2147</ext-link>. E-mail: Zorkaltsev@mail.ru </p></bio><bio xml:lang="en"><p>Maxim A. Zorkaltsev – MD, Doct. of Sci. (Med.), Associate Professor of the Radiology and Radiotherapy Department, Siberian State Medical University, Tomsk. <ext-link xlink:href="https://orcid.org/0000-0003-0025-2147" ext-link-type="uri">https://orcid.org/0000-0003-0025-2147</ext-link>. E-mail: Zorkaltsev@mail.ru</p></bio><email xlink:type="simple">Zorkaltsev@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8681-7892</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Траудт</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Traudt</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Траудт Алина Константиновна – канд. мед. наук, ассистент кафедры лучевой диагностики и лучевой терапии ФГБОУ ВО СибГМУ Минздрава России, Томск. https://orcid.org/0009-0001-8681-7892. E-mail: alina.traudt@yandex.ru </p></bio><bio xml:lang="en"><p>Alina K. Traudt – MD, Cand. of Sci. (Med.), Assistant of the Radiology and Radiotherapy Department, Siberian State Medical University, Tomsk. https://orcid.org/0009-0001-8681-7892. E-mail: alina.traudt@yandex.ru</p></bio><email xlink:type="simple">alina.traudt@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России; 634050 Томск, Московский тракт, д. 2, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Siberian State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГБОУ ВО “Сибирский государственный медицинский университет” Минздрава России; 634050 Томск, Московский тракт, д. 2, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Siberian State Medical University; 2, Moskovskii trakt, Tomsk 634050, Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>03</day><month>11</month><year>2024</year></pub-date><volume>28</volume><issue>4</issue><fpage>112</fpage><lpage>132</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ким Т., Завадовская В.Д., Дегтярев И.Ю., Замышевская М.А., Удодов В.Д., Зоркальцев М.А., Траудт А.К., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ким Т., Завадовская В.Д., Дегтярев И.Ю., Замышевская М.А., Удодов В.Д., Зоркальцев М.А., Траудт А.К.</copyright-holder><copyright-holder xml:lang="en">Kim T., Zavadovskaya V.D., Degtyarev I.Y., Zamishevskaya V.A., Udodov V.D., Zorkalcev M.S., Traudt A.K.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medvis.vidar.ru/jour/article/view/1382">https://medvis.vidar.ru/jour/article/view/1382</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: представить роль обзорной рентгенографии, ультразвуковое исследование (УЗИ), магнитно-резонансной томографии (МРТ), рутинной и двухэнергетической компьютерной томографии (ДЭКТ), а также остеосцинтиграфии в диагностике подагрического артрита. </p></sec><sec><title>Материал и методы</title><p>Материал и методы. Анализ литературных источников выполнялся в информационно-аналитических системах PubMed и Google Scholar за 2012–2023 гг. с использованием следующих ключевых слов: подагрический артрит, подагрический тофус, imaging of gout, X-ray study, ultrasound, CT, dual-energy CT, MRI, bone scintigraphy, PET/CT.</p></sec><sec><title>Результаты</title><p>Результаты. Проанализировано 894 статьи, 39 из которых использованы для составления обзора. Дополнительно использованы 42 статьи за 2018–2023 гг. и клинические рекомендации. Результаты поиска: статьи сгруппированы в блоки на основании лучевых модальностей, систематизирована визуальная картина и роль каждой модальности в ранней диагностике подагрического артрита.</p></sec><sec><title>Заключение</title><p>Заключение. Несмотря на то что “золотым стандартом” диагностики подагрического артрита является исследование синовиальной жидкости, основная роль в выявлении данного заболевания отводится лучевой диагностике.</p><p>Современные диагностические модальности – УЗИ, МРТ и ДЭКТ открывают новые возможности в выявлении подагры без необходимости инвазивной процедуры пункции сустава. Наибольшей диагностической информативностью обладают УЗИ и ДЭКТ, включенные в классификационные критерии ACR и EULAR.</p><p>ДЭКТ опережает в сравнительном аспекте другие лучевые модальности, при этом обеспечивает визуализацию кристаллов Моноурата натрия и их количественную оценку.</p><p>Результаты исследований, оценивающих чувствительность и специфичность современных методов визуализации, позволяют говорить о возможности адекватной и своевременной диагностике подагры. В то же время необходимо учитывать проблемы и ограничения используемых диагностических модальностей, что создают основу для дальнейших исследований в этом направлении.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to present modern methods of visualization of gouty tophi.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A search was made for scientific publications and clinical recommendations in the PubMed and Google Scholar information and analytical systems for 2007-2022, using the following words: diagnosis of gout, X-ray gout, gout ultrasound, gout CT, gout DECT, gout MRI, gout scintigraphy.</p></sec><sec><title>Results</title><p>Results. 894 articles were analyzed, 42 of which were used to compile the review. Search results - blocks of articles were created, within which the articles were analyzed to study diagnostic features.</p></sec><sec><title>Conclusion</title><p>Conclusion. Early diagnosis and the choice of the correct tactics for the treatment of gouty tophi remain extremely relevant and require additional attention from diagnostic doctors and clinicians.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>подагрический артрит</kwd><kwd>подагрический тофус</kwd><kwd>imaging of gout</kwd><kwd>X-ray study</kwd><kwd>ultrasound</kwd><kwd>CT</kwd><kwd>dual-energy CT</kwd><kwd>MRI</kwd><kwd>bone scintigraphy</kwd><kwd>PET/CT</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Gout</kwd><kwd>tophus</kwd><kwd>gout diagnostics</kwd><kwd>CT</kwd><kwd>MRI</kwd><kwd>DECT</kwd><kwd>ultrasound</kwd><kwd>X-ray</kwd><kwd>nuclear medicine.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chen-Xu M., Yokose C., Rai S.K. et al. 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