medvisМедицинская визуализацияMedical Visualization1607-07632408-9516RDS-Media Ltd.10.24835/1607-0763-1293medvis-1293Research ArticleСЕРДЦЕ И СОСУДЫHEART AND VESSELSПрогнозирование степени перегрузки правых камер сердца у пациентов с острой массивной тромбоэмболией легочной артерии на основании результатов КТ-диагностикиPrediction of the degree of the right heart chambers overload in patients with acute massive pulmonary embolism based on the results of MSCT diagnosticshttps://orcid.org/0000-0002-0504-1421СуховаМ. Б.SukhovaM. B.

Сухова Марина Борисовна – доктор мед. наук, профессор кафедры ядерной и экспериментальной медицины; заведующая рентгенодиагностическим отделением 

603950 Нижний Новгород, пр. Гагарина, д. 23;603005 Нижний Новгород, ул. Ванеева, 209

Marina B. Sukhova – Doct. of Sci. (Med.), radiologist 

23, Gagarin str., Nizhny Novgorod 603950;209, Vaneeva str., Nizhny Novgorod 603136

skkbnn@gmail.comhttps://orcid.org/0000-0003-4871-2341ТрофимоваТ. Н.TrofimovaT. N.

Трофимова Татьяна Николаевна – член-корр. РАН, доктор мед. наук, профессор, главный научный сотрудник 

197376 Санкт-Петербург, ул. Академика Павлова, 9

Tatiana N. Trofimova – Corresponding Member of the Russian Academy of Sciences, Doct. of Sci. (Med.), Professor, radiologist; Head of the laboratory of neuroimaging 

9 Akademic Pavlov str., St. Petersburg 197376

TTrofimova@sogaz-clinic.ruhttps://orcid.org/0000-0001-7150-7851ЯкимовВ. Н.YakimovV. N.

Якимов Василий Николаевич – доктор биол. наук, доцент, заведующий кафедрой экологии Института биологии и биомедицины 

603950 Нижний Новгород, пр. Гагарина, д. 23

Vasiliy N. Yakimov – Doct. of Sci. (Biol.), Head of the Department of Ecology 

23, Gagarin str., Nizhny Novgorod 603950

damselfly@yandex.ruhttps://orcid.org/0000-0001-9759-6477ВедуноваМ. В.VedunovaM. V.

Ведунова Мария Валерьевна – доктор биол. наук, профессор, директор 

603950 Нижний Новгород, пр. Гагарина, д. 23

Maria V. Vedunova – Doct. of Sci. (Biol.), Professor, Head of Institute of Biology and Biomedicine 

23, Gagarin str., Nizhny Novgorod 603950

mvedunova@yandex.ruКрюковаЕ. В.KryukovaE. V.

Крюкова Елена Владимировна – канд. мед. наук, врач-невролог отделения неврологии №2 

197376 Санкт-Петербург, ул. Академика Павлова, 9

Elena V. Kryukova – Cand. of Sci. (Med.), neurologist neurology department №2 

9 Akademic Pavlov str., St. Petersburg 197376

eldementyeva@gmail.comИнститут биологии и биомедицины ФГАОУ ВО “Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского”; ГБУЗ НО “Научный исследовательский институт – Специализированная кардиохирургическая клиническая больница им. академика Б.А. Королева”РоссияInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod; Scientific Research Institute – Specialized Cardiosurgical Clinical Hospital B.A. KorolevaRussian FederationФГБУН “Институт мозга человека им. Н.П. Бехтеревой РАН”РоссияN.P. Bechtereva Institute of the Human Brain of the Russian Academy of SciencesRussian FederationИнститут биологии и биомедицины ФГАОУ ВО “Национальный исследовательский Нижегородский государственный университет им. Н.И. Лобачевского”РоссияInstitute of Biology and Biomedicine, Lobachevsky State University of Nizhny NovgorodRussian Federation2023310720232744555Copyright © Сухова М.Б., Трофимова Т.Н., Якимов В.Н., Ведунова М.В., Крюкова Е.В., 20232023Сухова М.Б., Трофимова Т.Н., Якимов В.Н., Ведунова М.В., Крюкова Е.В.Sukhova M.B., Trofimova T.N., Yakimov V.N., Vedunova M.V., Kryukova E.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://medvis.vidar.ru/jour/article/view/1293

В группу исследования вошло 147 пациентов на этапе подготовки к экстренному хирургическому лечению острой массивной тромбоэмболии легочной артерии (ТЭЛА) в период с марта 2012 г. по декабрь 2019 г. включительно. В качестве КТ-показателей перегрузки правых камер сердца взяты обычные КТ-показатели, не требующие использования компьютерных томографов экспертного класса, ими стали верхняя полая вена, нижняя полая вена, непарная вена; рефлюкс контрастного препарата в нижнюю полую вену; рефлюкс контрастного препарата в печеночные вены. В ходе исследования проведен сравнительный анализ среднего давления в легочной артерии с вышеуказанными КТ-показателями. Наиболее устойчивую статистическую взаимосвязь с показателями среднего давления в легочной артерии продемонстрировали КТ-параметры – диаметр непарной вены и рефлюкс контрастного препарата в печеночные вены. По результатам работы предложена методика расчета фактических значений среднего давления в легочной артерии на основании КТ-параметра “диаметр непарной вены”.

The study group included 147 patients at the stage of preparation for emergency surgical treatment of acute massive PE in the period from March 2012 to December 2019 inclusive. As CT indicators of overload of the right chambers of the heart, the usual CT indicators that do not require the use of expert – class computed tomographs were taken – they were the superior vena cava, inferior vena cava, unpaired vein; reflux of the contrast drug into the inferior vena cava; reflux of the contrast drug into the hepatic veins. In the course of the study, a comparative analysis of the average pressure in the pulmonary artery with the above CT indicators was performed. The most stable statistical relationship with the indicators of mean pressure in the pulmonary artery was demonstrated by CT parameters – the diameter of the unpaired vein and the reflux of the contrast agent into the hepatic veins. Based on the results of the work, a method for calculating the actual values of the average pressure in the pulmonary artery based on the CT parameter of the diameter of the unpaired vein is proposed.

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The authors declare that there are no conflicts of interest present.